Department of Medical Physics and Bioengineering, University College London, Malet Place, Gower Street, London WC1E 6BT, UK.
Phys Med Biol. 2010 Jul 21;55(14):4169-85. doi: 10.1088/0031-9155/55/14/014. Epub 2010 Jul 5.
It is hoped that x-ray phase contrast imaging (XPCi) will provide a generational improvement in the effectiveness of mammography. XPCi is sensitive to the refraction which x-rays undergo as a result of the variation in x-ray propagation speeds within an object. XPCi is, however, seldom used in clinical applications owing mainly to a lack of suitable systems. The radiation physics group at UCL has previously designed and built an XPCi system sensitive to phase gradients in one dimension for application in security inspection. We present here the design methodology and final design of a prototype XPCi system sensitive to phase gradients in two directions for use in mammography. The technique makes efficient use of the flux available from a laboratory x-ray source, thus making it suitable for clinical use.
人们希望 X 射线相衬成像（XPCi）将为乳房 X 光检查的有效性带来质的飞跃。XPCi 对 X 射线在物体内部传播速度变化引起的折射很敏感。然而，由于缺乏合适的系统，XPCi 在临床应用中很少使用。UCL 的放射物理组之前设计并构建了一个一维 XPCi 系统，用于安全检查，该系统对相位梯度敏感。我们在此介绍了一种二维 XPCi 系统原型的设计方法和最终设计，该系统用于乳房 X 光检查。该技术有效地利用了实验室 X 射线源的通量，因此适合临床使用。
