Hoffstein V, Weiser W, Haney R
Department of Diagnostic Imaging, St. Michael's Hospital, Toronto, Canada.
Chest. 1991 Jul;100(1):81-5. doi: 10.1378/chest.100.1.81.
The purpose of this study was to examine whether a simple test, such as routine roentgenographic views of the upper airway, is useful in identifying anatomic narrowing of the airway in patients with sleep apnea. To accomplish this, we prospectively studied a group of 117 patients (95 male and 22 female subjects) referred for evaluation of heavy snoring and possible obstructive sleep apnea. All patients had full nocturnal polysomnography, including measurements of snoring. Lateral view of the airway obtained after swallowing contrast material was used to measure pharyngeal diameters at three sites along the airway. All measurements were performed with the patients standing and supine. We used three different definitions of sleep apnea (apnea/hypopnea index of 10, 20, and 40), and compared airway diameters between the apneic and nonapneic snorers. Only when sleep apnea was defined as greater than 40 apneas plus hypopneas per hour of sleep was there a significant difference in airway diameter at the tip of the palate and 1 cm distal to it between apneic and nonapneic snorers. Both groups of patients demonstrated a significant reduction in the retropalatal distance on assumption of the supine posture. Stepwise, forward, multiple linear regression analysis showed that the retropalatal distance and airway diameter at the tip of the palate and 1 cm distal to it were significant predictors of snoring, but not apnea. We conclude that (1) airway diameters account for some of the variability in snoring, and (2) they do not differentiate between apneic and nonapneic snorers.
本研究的目的是检验一项简单的检查,如气道上部的常规X线片,是否有助于识别睡眠呼吸暂停患者气道的解剖学狭窄。为实现这一目的,我们前瞻性地研究了一组117例患者(95例男性和22例女性受试者),他们因严重打鼾及可能的阻塞性睡眠呼吸暂停而前来接受评估。所有患者均进行了整夜多导睡眠监测,包括打鼾测量。吞咽造影剂后获得的气道侧位片用于测量气道三个部位的咽部直径。所有测量均在患者站立和仰卧位时进行。我们使用了三种不同的睡眠呼吸暂停定义(呼吸暂停/低通气指数分别为10、20和40),并比较了呼吸暂停打鼾者和非呼吸暂停打鼾者之间的气道直径。只有当睡眠呼吸暂停定义为每小时睡眠中呼吸暂停加低通气超过40次时,呼吸暂停打鼾者和非呼吸暂停打鼾者在腭尖及其远端1 cm处的气道直径才有显著差异。两组患者在仰卧位时腭后距离均显著减小。逐步向前多元线性回归分析表明,腭后距离以及腭尖及其远端1 cm处的气道直径是打鼾的显著预测因素,但不是呼吸暂停的预测因素。我们得出结论:(1)气道直径可解释打鼾的部分变异性;(2)它们无法区分呼吸暂停打鼾者和非呼吸暂停打鼾者。