Bull World Health Organ. 1962;26(6):745-58.
Mass oral vaccination of children against poliomyelitis was carried out in Poland in 1959 and 1960 with type 1 (CHAT strain) and type 3 (W-Fox) attenuated polioviruses. Altogether some 7 239 000 children 6 months through 14 years old received type 1 by May 1960 and nearly 6 818 500 children were fed type 3.Epidemiological observations indicate that the CHAT strain may safely be administered but that the W-Fox strain requires further investigation into the conditions in which it may be used for mass prophylaxis.The incidence of poliomyelitis in Poland decreased very considerably in 1960, the total incidence for that year (0.9 per 100 000) being almost 9 times lower than the median for the years 1951-59. Moreover, the usual summer-autumn epidemic outbreak did not occur in 1960.The efficacy of the vaccine (as calculated from the incidence of paralytic poliomyelitis among the vaccinated and among the unvaccinated) was evaluated at 86%.
1959 年和 1960 年,波兰对儿童进行了大规模的口服脊髓灰质炎疫苗接种,使用的是 1 型(CHA T 株)和 3 型(W-Fox 株)减毒脊髓灰质炎病毒。共有约 723.9 万名 6 个月至 14 岁的儿童在 1960 年 5 月前接种了 1 型疫苗,约有 681.85 万名儿童接种了 3 型疫苗。流行病学观察表明,CHA T 株可以安全使用,但 W-Fox 株需要进一步研究其在何种条件下可用于大规模预防。1960 年波兰脊髓灰质炎的发病率大幅下降,当年的总发病率(每 10 万人 0.9 例)比 1951-59 年的中位数低近 9 倍。此外,1960 年没有出现通常的夏秋季流行爆发。疫苗的效果(根据接种组和未接种组中麻痹性脊髓灰质炎的发病率计算)评估为 86%。