Bowring J, Tulloch I, Phadnis S V, Young M P A, Evans H, Walker P
Department of Obstetrics and Gynaecology, Royal Free Hospital, London, UK.
J Obstet Gynaecol. 2010;30(5):511-4. doi: 10.3109/01443615.2010.487580.
A small proportion of women require repeat treatments for cervical intraepithelial neoplasia (CIN). This study aimed to compare the effectiveness of two cervical excisional techniques offered within a London teaching hospital (large loop excision of the transformation zone (LLETZ) and laser cone biopsy) when carried out as secondary procedures. A significantly larger volume of tissue was excised following laser cone biopsy, however the depth of the specimen did not differ significantly. A trend for a larger percentage of secondary specimens, resulting in complete endo-cervical margins and a larger proportion of women achieving cytology negative for CIN post-treatment was shown within the laser cone biopsy group.
一小部分女性需要对宫颈上皮内瘤变（CIN）进行重复治疗。本研究旨在比较伦敦一家教学医院提供的两种宫颈切除技术（转化区大环形切除术（LLETZ）和激光锥形活检）作为二次手术时的有效性。激光锥形活检后切除的组织量明显更大，然而标本的深度没有显著差异。激光锥形活检组显示出一种趋势，即二次标本的百分比更大，导致宫颈内边缘完整，且治疗后CIN细胞学阴性的女性比例更高。
