Falcao-Reis F M, Hogg C R, Frumkes T E, Arden G B
Department of Ophthalmology, Oporto Medical School, Portugal.
Eye (Lond). 1991;5 ( Pt 1):138-44. doi: 10.1038/eye.1991.25.
Twenty-nine patients with exaggerated rod-cone interaction are described. All were referred because they appeared to suffer from night blindness. ERG and EOGs were performed but were normal. However, investigation with a modified dark-adaptometry technique showed that in these patients cone flicker thresholds rise considerably more during dark adaptation than is normal, and this is sufficient to explain the symptoms. In one case, the condition appears familial. Many patients report their symptoms begin in early adult life and slowly get worse, but we have no objective evidence of progression.
本文描述了29例具有过度视杆-视锥细胞相互作用的患者。他们均因疑似患有夜盲症前来就诊。虽然进行了视网膜电图（ERG）和眼电图（EOG）检查，但结果均正常。然而，采用改良的暗适应测量技术进行检查发现，这些患者在暗适应过程中视锥细胞闪烁阈值的升高幅度远高于正常水平，而这足以解释其症状。在其中一例中，该病表现出家族性。许多患者报告其症状始于成年早期并逐渐加重，但我们没有病情进展的客观证据。
