肠内营养对创伤患者氮平衡的影响
Impact of enteral nutrition on nitrogen balance in patients of trauma.
作者信息
Jivnani Sabita, Iyer Sandhya, Umakumar Kabeer, Gore M A
机构信息
Department of Surgery, LTMGH & LTMMC, Sion, Mumbai, India.
出版信息
J Emerg Trauma Shock. 2010 Apr;3(2):109-14. doi: 10.4103/0974-2700.62101.
BACKGROUND
A prospective study of 50 patients of trauma was carried out at a tertiary level trauma center in Mumbai. The aim was to study the hypermetabolic response to trauma and the effect of early enteral feeding and nutritional supplementation in blunting this response in these patients.
METHODS
Early enteral feeding was started within 72 h in most patients. The caloric requirement was calculated as per the body weight and a 150: 1 ratio of nonprotein calories to protein was maintained. A 24-h urinary nitrogen loss was estimated and nitrogen balance was calculated on days 1, 3 and 7.
RESULTS
The correlation between the injury severity and the severity of catabolism was also analysed. Urinary nitrogen loss and nitrogen balance were used as parameters to evaluate the hypermetabolic response.
CONCLUSIONS
Early (within 72 h) enteral nutritional support blunts this hypermetabolic response to some extent in these trauma patients.
背景
在孟买的一家三级创伤中心对50例创伤患者进行了一项前瞻性研究。目的是研究创伤后的高代谢反应以及早期肠内喂养和营养补充对减轻这些患者这种反应的效果。
方法
大多数患者在72小时内开始早期肠内喂养。根据体重计算热量需求，并维持非蛋白质热量与蛋白质150:1的比例。估计24小时尿氮损失，并在第1、3和7天计算氮平衡。
结果
还分析了损伤严重程度与分解代谢严重程度之间的相关性。尿氮损失和氮平衡用作评估高代谢反应的参数。
结论
早期（72小时内）肠内营养支持在一定程度上减轻了这些创伤患者的这种高代谢反应。
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