Ignjatović Nebojsa, Vasiljević Marina, Milić Dragan, Stefanović Jelena, Stojanović Miroslav, Karanikolić Aleksandar, Zlatić Aleksandar, Djordjević Goran, Zivić Sasa, Jeremić Ljiljana, Djordjević Ivona, Janković Radmilo
Surgical Clinic, Clinical Centre, Nis, Serbia.
Srp Arh Celok Lek. 2010 May-Jun;138(5-6):300-4. doi: 10.2298/sarh1006300i.
Chronic arterial insufficiency (CAI) of lower extremities is important socio-economical and healthcare problem, due to its high incidence of morbidity, disability and mortality.
The aim of our work was to determine the diagnostic importance of pulse oximetry in the early detection of stage of lower extremities CAI based on peripheral arterial oxygen saturation of haemoglobin (SpO2).
Prospectively, we analyzed a group of 50 patients, admitted at the Vascular Department of Surgical Clinic in Nis during the period from September 2006 to October 2007, with evident symptoms and signs of different stages of lower extremities CAI verified by ultrasonography. In patients with lower extremity disorder of tissue arterial capillaries, SpO2 was determined by pulse oximetry.
Using pulse oximetry, depending on the of stage of lower extremities CAI, we revealed a considerable difference in the stages of functional ischemia SpO2: Fontaine I - 95.33 +/- 1.41%, Fontaine IIa - 92.14 +/- 2.27% and Fontaine IIb - 79.67 +/- 2.73%; in stage critical ischemia SpO2: Fontaine III - 62.54 +/- 4.39% and Fontaine IV - 47.67 +/- 6.16%. In 3 patients with gangrenous foot and fingers SpO2 was immeasurable and progressive decrease in SpO2 of arterial capillaries (p < 0.01 between stages).
Due to the reliability and simplicity of pulse oximetry it can be a routinely used diagnostic device for patients with early determined stage of lower extremities CAI.
下肢慢性动脉供血不足（CAI）是一个重要的社会经济和医疗保健问题，因其发病率、致残率和死亡率都很高。
我们研究的目的是基于血红蛋白外周动脉血氧饱和度（SpO2）来确定脉搏血氧饱和度测定法在早期检测下肢CAI阶段中的诊断重要性。
前瞻性地，我们分析了一组50例患者，这些患者于2006年9月至2007年10月期间入住尼什外科诊所血管科，有下肢CAI不同阶段的明显症状和体征，经超声检查证实。对于有下肢组织动脉毛细血管紊乱的患者，通过脉搏血氧饱和度测定法测定SpO2。
使用脉搏血氧饱和度测定法，根据下肢CAI的阶段，我们发现在功能性缺血阶段SpO2有显著差异：Fontaine I期为95.33±1.41%，Fontaine IIa期为92.14±2.27%，Fontaine IIb期为79.67±2.73%；在严重缺血阶段SpO2：Fontaine III期为62.54±4.39%，Fontaine IV期为47.67±6.16%。在3例患有坏疽足和手指的患者中，SpO2无法测量，且动脉毛细血管的SpO2呈进行性下降（各阶段之间p<0.01）。
由于脉搏血氧饱和度测定法的可靠性和简便性，它可以成为下肢CAI早期确诊患者的常规诊断设备。
