Seligman Neil S, Sbar Wingkan, Berghella Vincenzo
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA, USA.
J Matern Fetal Neonatal Med. 2011 Mar;24(3):525-30. doi: 10.3109/14767058.2010.494745. Epub 2010 Jul 7.
To estimate the risk of gastrointestinal and pouch complications and alterations in pouch function related to pregnancy in women treated with ileal pouch-anal anastomosis (IPAA).
Pregnancies following IPAA were identified in our center, and in the literature through MEDLINE and PUBMED searches. The incidence of each complication was calculated. Pouch function was compared before and after pregnancy, by mode of delivery, and between women who became pregnant versus those that did not.
The incidence of complications in 283 pregnancies after IPAA was 12.7% including antepartum (2.8%) or postpartum (6.7%) small bowel obstruction, pouchitis (1.8%), and perianal abscess (0.4%). Stool frequency and incontinence were not significantly affected by pregnancy or mode of delivery.
Pregnancy after IPAA is overall safe, associated with limited complications and no significant alteration in pouch function. Vaginal delivery appears as safe as cesarean section for most women.
评估接受回肠储袋肛管吻合术（IPAA）治疗的女性妊娠相关的胃肠道及储袋并发症风险以及储袋功能改变。
通过在本中心以及通过检索MEDLINE和PUBMED在文献中识别IPAA术后妊娠情况。计算每种并发症的发生率。比较妊娠前后、不同分娩方式以及妊娠女性与未妊娠女性之间的储袋功能。
IPAA术后283次妊娠的并发症发生率为12.7%，包括产前（2.8%）或产后（6.7%）小肠梗阻、储袋炎（1.8%）和肛周脓肿（0.4%）。排便频率和大便失禁未受妊娠或分娩方式的显著影响。
IPAA术后妊娠总体安全，并发症有限，储袋功能无显著改变。对大多数女性而言，阴道分娩似乎与剖宫产一样安全。
