西班牙裔社区健康研究/拉丁裔研究的设计与实施。
Design and implementation of the Hispanic Community Health Study/Study of Latinos.
机构信息
Division of Cardiovascular Sciences, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
出版信息
Ann Epidemiol. 2010 Aug;20(8):629-41. doi: 10.1016/j.annepidem.2010.03.015.
PURPOSE
The Hispanic Community Health Study (HCHS)/Study of Latinos (SOL) is a comprehensive multicenter community based cohort study of Hispanics/Latinos in the United States.
METHODS
The Study rationale, objectives, design, and implementation are described in this report.
RESULTS
The HCHS/SOL will recruit 16,000 men and women who self-identify as Hispanic or Latino, 18 to 74 years of age, from a random sample of households in defined communities in the Bronx, Chicago, Miami, and San Diego. The sites were selected so that the overall sample would consist of at least 2000 persons in each of the following origin designations: Mexican, Puerto Rican and Dominican, Cuban, and Central and South American. The study includes research in the prevalence of and risk factors for heart, lung, blood and sleep disorders, kidney and liver function, diabetes, cognitive function, dental conditions, and hearing disorders.
CONCLUSIONS
The HCHS/SOL will (1) characterize the health status and disease burden in the largest minority population in the United States; (2) describe the positive and negative consequences of immigration and acculturation of Hispanics/Latinos to the mainstream United States life-styles, environment and health care opportunities; and (3) identify likely causal factors of many diseases in a population with diverse environmental exposures, genetic backgrounds, and early life experiences.
目的
西班牙裔美国人健康研究（HCHS）/拉丁裔研究（SOL）是一项针对美国西班牙裔/拉丁裔人群的综合、多中心、基于社区的队列研究。
方法
本报告介绍了该研究的原理、目标、设计和实施情况。
结果
HCHS/SOL 将从布朗克斯、芝加哥、迈阿密和圣地亚哥的指定社区中随机抽取 16000 名年龄在 18 至 74 岁之间的自认为是西班牙裔或拉丁裔的男性和女性进行招募。选择这些地点是为了使总体样本至少包括以下原籍国的 2000 人：墨西哥、波多黎各和多米尼加、古巴，以及中美洲和南美洲。该研究包括对心脏、肺部、血液和睡眠障碍、肾脏和肝脏功能、糖尿病、认知功能、牙齿状况和听力障碍的流行率和风险因素进行研究。
结论
HCHS/SOL 将：（1）描述美国最大少数族裔人群的健康状况和疾病负担；（2）描述西班牙裔/拉丁裔移民和融入美国主流生活方式、环境和医疗保健机会的积极和消极后果；（3）在一个具有多样化环境暴露、遗传背景和早期生活经历的人群中确定许多疾病的可能因果因素。
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