Department of Crop & Soil Sciences, and Institute for Plant Breeding, Genetics & Genomics, 111 Riverbend Road, University of Georgia, Athens, GA 30602-6810, USA.
N Biotechnol. 2010 Nov 30;27(5):545-51. doi: 10.1016/j.nbt.2010.05.016. Epub 2010 May 31.
Myths abound when it comes to GE crops. At their worst, myths play an active role in discouraging the use of GE to solve problems that afflict humankind, such as malnutrition and birth defects. Of all the various myths, two have been particularly important in preventing the use of GE maize in its areas of origin. The first is that transgenic maize will contaminate and destroy land races, thus destroying biodiversity and its associated cultural traditions. This myth totally ignores the fact that the gene flow that has taken place between maize and its progenitor, between the land races, and between land races and modern hybrids, has not led to any dire consequences. The second myth is that crops are natural and have not been modified by humans, or if they have, that plant breeding does not alter DNA. This myth ignores the fact that for the most part, it is impossible to alter the appearance of crops without changing the DNA. In fact, DNA movement within the crop genome is normal and its movement leads to double-strand DNA repair, with results like those found around transgene insertion sites. In addition, plants have ways to create novel genes. These changes help plants adapt to evolution and to human selection. The net result is that changes similar to what happens during the production of engineered plants takes place anyway in plant genomes.
当涉及到转基因作物时,存在着许多神话。在最坏的情况下,这些神话会积极地阻止人们利用转基因技术来解决困扰人类的问题,如营养不良和出生缺陷。在所有各种神话中,有两个在阻止转基因玉米在其起源地使用方面尤其重要。第一个神话是,转基因玉米会污染和破坏地方品种,从而破坏生物多样性及其相关的文化传统。这个神话完全忽略了一个事实,即玉米与其祖先、地方品种之间以及地方品种与现代杂交品种之间已经发生了基因流动,但并没有导致任何可怕的后果。第二个神话是,作物是天然的,没有被人类改变,或者即使被改变了,植物育种也不会改变 DNA。这个神话忽略了一个事实,即在大多数情况下,要想改变作物的外观而不改变 DNA 是不可能的。事实上,作物基因组内的 DNA 运动是正常的,它的运动导致双链 DNA 修复,其结果与转基因插入位点周围的结果相似。此外,植物有创造新基因的方法。这些变化有助于植物适应进化和人类的选择。最终的结果是,类似工程植物生产过程中发生的变化无论如何都会在植物基因组中发生。