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产妇产后抑郁与儿童超重。

Maternal postpartum distress and childhood overweight.

机构信息

Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark.

出版信息

PLoS One. 2010 Jun 30;5(6):e11136. doi: 10.1371/journal.pone.0011136.

Abstract

OBJECTIVE

We investigated associations between maternal postpartum distress covering anxiety, depression and stress and childhood overweight.

METHODS

We performed a prospective cohort study, including 21,121 mother-child-dyads from the Danish National Birth Cohort (DNBC). Maternal distress was measured 6 months postpartum by 9 items covering anxiety, depression and stress. Outcome was childhood overweight at 7-years-of age. Multiple logistic regression analyses were performed and information on maternal age, socioeconomic status, pre-pregnancy BMI, gestational weight gain, parity, smoking during pregnancy, paternal BMI, birth weight, gestational age at birth, sex, breastfeeding and finally infant weight at 5 and 12 month were included in the analyses.

RESULTS

We found, that postpartum distress was not associated with childhood risk of overweight, OR 1.00, 95%CI [0.98-1.02]. Neither was anxiety, depression, or stress exposure, separately. There were no significant differences between the genders. Adjustment for potential confounders did not alter the results.

CONCLUSION

Maternal postpartum distress is apparently not an independent risk factor for childhood overweight at 7-years-of-age. However, we can confirm previous findings of perinatal determinants as high maternal pre-pregnancy BMI, and smoking during pregnancy being risk factors for childhood overweight.

摘要

目的

我们调查了产妇产后焦虑、抑郁和压力等困扰与儿童超重之间的关联。

方法

我们进行了一项前瞻性队列研究,纳入了来自丹麦国家出生队列(DNBC)的 21121 对母婴对子。产后 6 个月通过 9 项涵盖焦虑、抑郁和压力的项目来测量产妇的困扰。结局是 7 岁时儿童超重。采用多因素逻辑回归分析,并纳入了母亲年龄、社会经济地位、孕前 BMI、孕期体重增加、产次、孕期吸烟、父亲 BMI、出生体重、出生时胎龄、性别、母乳喂养以及婴儿 5 个月和 12 个月时的体重等信息。

结果

我们发现,产后困扰与儿童超重风险无关,OR 1.00,95%CI [0.98-1.02]。焦虑、抑郁或压力暴露也没有差异。性别之间没有显著差异。调整潜在混杂因素后,结果未发生改变。

结论

产妇产后困扰似乎不是 7 岁儿童超重的独立危险因素。然而,我们可以证实先前发现的围产期决定因素,如母亲孕前 BMI 高和孕期吸烟,是儿童超重的危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f4b/2894862/df6d15299260/pone.0011136.g001.jpg

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