Bikanga Raphaël, Makani Thomas, Agnaniet Huguette, Obame Louis Clément, Abdoul-Latif Fatouma Mohamed, Lebibi Jacques, Menut Chantal
Laboratoires de Substances Naturelles et de Synthèses Organométallique (LASNSOM), Université des Sciences et Techniques de Masuku B.P. 943, Franceville, Gabon.
Nat Prod Commun. 2010 Jun;5(6):961-4.
Water-distilled essential oils from leaves and bark of Santiria trimera (Oliv.) Aubrév. (Burseraceae) collected in Gabon were analyzed using capillary GC-FID and GC-MS. The leaf essential oil, which is described for the first time, was dominated by sesquiterpenes (76.5%), among which alpha-humulene (34.6%) and beta-caryophyllene (14.9%) were the major components. The bark essential oil was almost exclusively monoterpenic, with alpha-pinene (51.5%) and alpha-terpineol (16.8%) as main constituents. The antimicrobial activities of both essential oils were tested against eight Gram-positive and three Gram-negative bacteria by using agar disc diffusion and broth microdilution methods; anticandidal effect was also tested on different strains of Candida albica. The Gram-negative bacteria were the less sensitive to the leaf essential oil, which was effective against Bacillus cereus and Enterococcus faecalis. The bark essential oil was more active and, in particular, exhibited significant antimicrobial activity against Proteus mirabilis, which was resistant to the leaf oil. A weak anticandidal effect of both essential oils was observed.
对在加蓬采集的三裂山榄（Santiria trimera (Oliv.) Aubrév.，橄榄科）树叶和树皮经水蒸馏得到的精油，采用毛细管气相色谱 - 火焰离子化检测器（GC - FID）和气相色谱 - 质谱联用仪（GC - MS）进行分析。首次报道的树叶精油以倍半萜类为主（76.5%），其中α - 葎草烯（34.6%）和β - 石竹烯（14.9%）为主要成分。树皮精油几乎全是单萜类，主要成分是α - 蒎烯（51.5%）和α - 松油醇（16.8%）。采用琼脂平板扩散法和肉汤微量稀释法测试了两种精油对8种革兰氏阳性菌和3种革兰氏阴性菌的抗菌活性；还对不同白色念珠菌菌株测试了抗念珠菌效果。革兰氏阴性菌对树叶精油较不敏感，树叶精油对蜡样芽孢杆菌和粪肠球菌有效。树皮精油活性更强，尤其对奇异变形杆菌表现出显著抗菌活性，而奇异变形杆菌对树叶精油耐药。两种精油均观察到较弱的抗念珠菌效果。
