Department of Organic Chemistry for Life Science, Kobe Pharmaceutical University, 4-19-1, Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan.
Org Lett. 2010 Aug 6;12(15):3506-9. doi: 10.1021/ol101365x.
Switchable access to dihydropyrazoles and pyrazoles has been developed from common hydrazides by reagent-controlled iodocyclization. Controlling the oxidative aromatization in iodocyclization for heterocycles is reported for the first time, and this methodology maximally utilizes the dual nature of iodine.
通过试剂控制的碘环化反应，从常见的酰肼出发开发了二氢吡唑和吡唑的可切换途径。本文首次报道了控制碘环化中环的氧化芳构化，这种方法最大限度地利用了碘的双重性质。
