Liou S W, Yen R J
Department of Ophthalmology, Jen-Ai Municipal Hospital, Taipei, Taiwan, Republic of China.
J Ocul Pharmacol. 1991 Spring;7(1):77-81. doi: 10.1089/jop.1991.7.77.
Topical use of Indomethacin was documented to prevent surgically induced miosis, and it reduced postoperative inflammatory response. We collected 26 consecutive cataract eyes. Seventeen eyes in the study group received topical 0.1% Indomethacin eyedrops from one day before surgery until two weeks after surgery, in addition to the routine medications. Nine eyes belonging to the control group received the routine medications only. The parameters of our study included the measurement of the pupil diameters in surgery, the central corneal thickness, the intraocular pressure, and the anterior chamber reaction before and after surgery. The results revealed that topical use of 0.1% Indomethacin eyedrops could prevent intraoperative miosis and reduce postoperative corneal edema and anterior chamber reaction, but it did not show much influence on intraocular pressure.
吲哚美辛局部应用被证明可预防手术引起的瞳孔缩小，并减轻术后炎症反应。我们收集了连续26只白内障眼。研究组的17只眼在术前一天至术后两周除常规用药外，还接受局部0.1%吲哚美辛滴眼液治疗。对照组的9只眼仅接受常规用药。我们研究的参数包括手术中瞳孔直径的测量、中央角膜厚度、眼压以及手术前后的前房反应。结果显示，局部使用0.1%吲哚美辛滴眼液可预防术中瞳孔缩小，并减轻术后角膜水肿和前房反应，但对眼压影响不大。
