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[17β-雌二醇对蝾螈腺垂体生长激素细胞的作用(作者译)]

[Effect of estradiol-17 beta on the somatrotroph cells of the adenohypophysis in the newt (author's transl)].

作者信息

Andrieux B

出版信息

Ann Endocrinol (Paris). 1977;38(6):375-6.

PMID:206180
Abstract

The somatotroph cells of the female newt's adenohypophysis are characterized by PAS positive, acidophils, electron dense large inclusions (4-6 micrometer). The apparition of these inclusions has been studied in females during the puberty. A correlation between the ovary stages and apparition, number and ultrastructural aspects (paracrystalline arrangement) of the inclusions is established. Same inclusion genesis and aspects has been observed after treatment of young newt males by oestradiol-17 beta (5 mg/liter diluted in the aquarium water). It is concluded that endocrine activity of ovaries may be responsible of the inclusions occurence in the females.

摘要

雌性蝾螈腺垂体的生长激素细胞的特征为过碘酸雪夫反应(PAS)阳性、嗜酸性、电子密度高的大包涵体(4-6微米)。已对青春期雌性蝾螈的这些包涵体的出现情况进行了研究。建立了卵巢阶段与包涵体的出现、数量及超微结构方面(准晶体排列)之间的相关性。在用17β-雌二醇(5毫克/升,溶于水族箱水中)处理幼年雄性蝾螈后,观察到了相同的包涵体形成及特征。得出的结论是,卵巢的内分泌活动可能是雌性蝾螈中出现包涵体的原因。

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