Department of Surgical Oncology, Medical School of Crete-University Hospital, Herakleion, Greece.
Int J Dermatol. 2010 Jul;49(7):806-9. doi: 10.1111/j.1365-4632.2009.04305.x.
Basal cell carcinoma (BCC) is very common and usually encountered when it is small in size. Giant BCC (i.e. greater than 5 cm in diameter) is quite rare and comprises 0.5 percent of all BCC. Extremely rarely, tumors larger than 20 cm have been reported. Herein, a case with an enormous, vegetating BCC of the abdominal wall, 30 x 20 cm in size, is described. This report demonstrates that such a case can still be observed in the civilized world of the 21st century, which remains profoundly astonishing. A literature survey was performed and revealed only 7 cases with such super giant BCC (i.e. larger than 20 cm in diameter). Generally, this tumor attains these enormous proportions due to neglect on the patient's part, and is usually located at sites covered by clothes. Treatment is mainly surgical and generally curative, resulting also in an improved quality of life. Tumor size of more than 10 cm in diameter is associated with increased risk for metastatic disease, severe morbidity and consequently impaired prognosis.
基底细胞癌(BCC)非常常见,通常在其体积较小时被发现。巨型 BCC(即直径大于 5 厘米)则相当罕见,占所有 BCC 的 0.5%。极罕见的情况下,报道的肿瘤直径超过 20 厘米。在此,描述了一例腹壁巨大、有蒂的 BCC,大小为 30x20 厘米。本报告表明,在 21 世纪的文明世界中,仍会观察到如此巨大的病例,这令人深感震惊。进行了文献调查,仅发现 7 例如此超大巨型 BCC(即直径大于 20 厘米)的病例。通常,由于患者的忽视,此类肿瘤会达到如此巨大的体积,且通常位于衣服覆盖的部位。治疗主要是手术,通常可治愈,并提高生活质量。直径超过 10 厘米的肿瘤与转移疾病风险增加、严重发病率以及预后受损相关。