Rudić Milan, Kranjcec Zoran, Lisica-Sikić Natasa, Kovacić Marijan
Zadar General Hospital, Department of Otorhinolaryngology and Head and Neck Surgery, Zadar, Croatia.
Coll Antropol. 2012 Mar;36(1):317-9.
Giant basal cell carcinoma (GBCC) is defined as a tumor 5cm or greater in diameter. They present less than 1% of all basal cell carcinomas. We present a case of an 85-year-old male patient with a giant ulcerating tumor of the left forehead (measuring 7x6 cm). Under local anesthesia tumor was surgically excised. No involvement of the underlying periostal or bone structure was noted. Pathohystological exam revealed the giant basal cell carcinoma, with free surgical margins. Giant basal cell carcinomas are rare tumors and are usually result of a long duration and patient neglect. In comparison to the ordinary basal cell carcinoma these tumors have a higher metastatic potential. Surgical resection with negative surgical margin is the best possible treatment option.
巨大基底细胞癌（GBCC）定义为直径5厘米或更大的肿瘤。它们在所有基底细胞癌中所占比例不到1%。我们报告一例85岁男性患者，其左前额有一个巨大溃疡性肿瘤（尺寸为7×6厘米）。在局部麻醉下对肿瘤进行了手术切除。未发现下方骨膜或骨质结构受累。病理组织学检查显示为巨大基底细胞癌，手术切缘阴性。巨大基底细胞癌是罕见肿瘤，通常是病程长且患者未重视的结果。与普通基底细胞癌相比，这些肿瘤具有更高的转移潜能。手术切缘阴性的手术切除是最佳治疗选择。
