Department of Dermatology, University Hospital Basel, Basel, Switzerland.
J Am Acad Dermatol. 2011 May;64(5):974-80. doi: 10.1016/j.jaad.2009.11.013. Epub 2010 Jul 8.
In the digital age, personal identification by fingerprints (epidermal ridges) has become more frequent and is often required for biometric passports. The more fingerprints are analyzed, the more variants in their formation are documented. Individuals completely missing fingerprints as an isolated finding are extremely rare. Only 4 kindreds have been described to date, with additional clinical features in most cases. We describe a female patient with missing epidermal ridges on the fingers, palms, toes, and soles as an isolated feature. Absent fingerprints, or adermatoglyphia, were inherited over 4 generations of her family in an autosomal dominant fashion. We present the clinical features of the index patient, and compare the case with previous reports in the literature. Because of problems in personal identification, this embryologic malformation caused the patient significant difficulties when traveling to other countries, which is why we name it the immigration delay disease.
在数字时代，通过指纹（表皮嵴）进行个人识别变得更加频繁，生物识别护照通常也需要进行指纹识别。对指纹进行的分析越多，其形成的变体就记录得越多。完全没有指纹作为孤立发现的个体极为罕见。迄今为止，只有 4 个家族被描述过，大多数情况下还有其他临床特征。我们描述了一名女性患者，其手指、手掌、脚趾和脚底的表皮嵴缺失，这是一个孤立的特征。在她的家族中，缺失指纹（或无皮纹症）通过常染色体显性遗传跨越了 4 代。我们呈现了该索引患者的临床特征，并与文献中的先前报告进行了比较。由于个人识别方面的问题，这种胚胎发育畸形导致患者在前往其他国家时遇到了重大困难，这就是我们将其命名为移民延迟疾病的原因。
