GKT Cancer Reconstructive Service, St.Thomas' Hospital, Westminster Bridge Road, London, UK.
Breast. 2011 Feb;20(1):21-5. doi: 10.1016/j.breast.2010.06.006. Epub 2010 Jul 8.
Skin sparing mastectomy (SSM) followed by immediate breast reconstruction (IBR) is not only oncologically safe but provides also significant benefits both cosmetically and functionally. The superiority of this technique can only be fully established, however, by developing a framework for minimising complications. The present study seeks to elucidate the key factors affecting outcome.
Data for all skin sparing mastectomies with immediate autologous and implant based reconstructions, performed in a three year period (2006-2008) was retrospectively collated. Complications were classified into major and minor. Patients were excluded who had flap loss due to vascular complications.
The total number analysed was 151. 17.2% had major complications, 23% had minor and 61% had no complications. The Wise and the "tennis" incision had significantly higher rates of wound dehiscence when compared with the periareolar incision (p = 0.025, p = 0.098). There was no significant difference between diathermy or blade dissection techniques, or the use of subcutaneous adrenaline infiltration. Increasing BMI was associated with increased skin flap necrosis and wound dehiscence, and an excised breast mass of greater than 750 g and a sternal notch to nipple length of greater than 26 cm are associated as well with increased flap-related complications (p = 0.0002, p = 0.0049).
Factors such as Wise pattern and tennis racquet incision, BMI and breast mass and sternal notch to nipple length adversely affect skin sparing mastectomy flap morbidity. These factors should be factored in to patient selection and operative planning especially for obese and large breasted women undergoing skin sparing mastectomy with immediate breast reconstruction.
阐明影响乳房重建术皮瓣并发症的关键因素。
回顾性分析了 3 年间(2006 年至 2008 年)所有接受即刻自体和植入物乳房重建的保留皮肤乳房切除术患者的数据。将并发症分为主要和次要并发症。因血管并发症导致皮瓣坏死的患者被排除在外。
共分析了 151 例患者,其中 17.2%的患者发生了主要并发症,23%的患者发生了次要并发症,61%的患者无并发症。与乳晕切口相比,Wise 切口和“网球拍”切口的切口裂开率明显更高(p=0.025,p=0.098)。电刀或刀片解剖技术、皮下肾上腺素浸润的使用与皮瓣坏死或切口裂开的发生率之间无显著差异。BMI 增加与皮瓣坏死和切口裂开的风险增加有关,切除的乳房组织大于 750g 和胸骨切迹到乳头的长度大于 26cm 也与皮瓣相关并发症的增加有关(p=0.0002,p=0.0049)。
Wise 型和网球拍型切口、BMI、乳房组织大小和胸骨切迹到乳头的长度等因素会增加保留皮肤乳房切除术皮瓣的发病率。在选择患者和进行手术规划时,应考虑这些因素,特别是对于接受保留皮肤乳房切除术和即刻乳房重建的肥胖和大乳房女性。