二尖瓣狭窄时左心房顺应性及左心房容积的临床研究

Clinical study of left atrial compliance and left atrial volume in mitral stenosis.

作者信息

Sato S, Kawashima Y, Hirose H, Nakano S, Matsuda H, Shimasaki Y

机构信息

First Department of surgery, Osaka University Medical School, Japan.

出版信息

Jpn Circ J. 1991 May;55(5):481-6. doi: 10.1253/jcj.55.481.

DOI:10.1253/jcj.55.481

PMID:2061998

Abstract

We studied left atrial compliance and left atrial volume in 21 patients with mitral stenosis showing a normal sinus rhythm. 1) A significant (p less than 0.001) negative linear correlation of r = 0.72 was found between the mitral valve area (MVA) and left atrial mean pressure (LAm). 2) A significant (p less than 0.005) positive linear correlation of r = 0.60 was found between MVA and left atrial compliance (delta V/delta P). 3) A significant (p less than 0.001) hyperbolic correlation of r = 0.73 was found between LAm and delta V/delta P. 4) A significant (p less than 0.001) hyperbolic correlation of r = 0.65 was found between left atrial specific compliance (delta V/delta P/LAVmax. LAVmax: left atrial maximum volume) and left atrial mean volume. 5) These findings led to the conclusion that in patients with mitral stenosis showing a normal sinus rhythm, left atrial compliance was decreased in patients whose left atrial volume was increased, and the decrease of left atrial compliance was related to narrowing of the mitral valve area and elevation of the left atrial pressure.

摘要

我们对21例窦性心律正常的二尖瓣狭窄患者的左心房顺应性和左心房容积进行了研究。1）二尖瓣瓣口面积（MVA）与左心房平均压（LAm）之间存在显著（p<0.001）的负线性相关，r=0.72。2）MVA与左心房顺应性（ΔV/ΔP）之间存在显著（p<0.005）的正线性相关，r=0.60。3）LAm与ΔV/ΔP之间存在显著（p<0.001）的双曲线相关，r=0.73。4）左心房比顺应性（ΔV/ΔP/LAVmax，LAVmax：左心房最大容积）与左心房平均容积之间存在显著（p<0.001）的双曲线相关，r=0.65。5）这些发现得出结论，在窦性心律正常的二尖瓣狭窄患者中，左心房容积增加的患者左心房顺应性降低，左心房顺应性的降低与二尖瓣瓣口面积缩小和左心房压力升高有关。