Service de Radiologie et Imagerie Médicale, Centre Hospitalier Universitaire Purpan, Place du Dr Baylac, TSA 40031, 31059 Toulouse Cedex 9, France.
Eur J Radiol. 2011 Nov;80(2):e176-81. doi: 10.1016/j.ejrad.2010.06.002. Epub 2010 Jul 10.
To validate quantitative and qualitative criteria of normal healthy skin using high-resolution MR imaging.
FIESTA and spin echo sequences of the skin of the heel, back and calf were obtained in 31 healthy volunteers. A dedicated 3-in. coil for study of the skin was used to optimize reception sensitivity. Quantitative analysis was performed to measure skin thickness in these three sites and qualititative analysis aimed to differentiate the various skin layers.
With both sequences, the stratum corneum appeared as a hyperintense layer. The epidermis was visualized appeared as a fine, homogeneous, hyperintense line. The dermoepidermal junction was clearer particularly in the calf. The dermis was also identified in each sequence and in each anatomic site. The signal was hypointense in both sequences, homogeneous with spin echo and more heterogeneous with FIESTA. Moreover the interface between the papillary and the reticular dermis could be distinguished. The hypodermis was visualized in both sequences and in all sites and hypodermal inclusions in the dermis were seen particularly in the back and calf. Lastly, the pilosebaceous follicles and the deep vascular network of the reticular dermis were more clearly seen with FIESTA sequence. Measures of overall skin thickness and for each layer according to site, sex and MRI sequence were performed. Statistical analysis was then performed to seek significant differences between the results according to these parameters.
MR imaging provides global analysis with high resolution of the various skin layers down to the hypodermis and the muscular fascia.
利用高分辨率磁共振成像技术对正常健康皮肤的定量和定性标准进行验证。
对 31 名健康志愿者的足跟、背部和小腿皮肤进行 FIESTA 和自旋回波序列扫描。使用专用的 3 英寸皮肤线圈来优化接收灵敏度。进行定量分析以测量这三个部位的皮肤厚度，定性分析旨在区分不同的皮肤层。
两种序列下，角质层均表现为高亮信号层。表皮显示为精细、均匀的高亮线。真皮表皮交界处在小腿处更为清晰。两种序列和每个解剖部位均能识别出真皮。信号在两种序列下均为低信号，自旋回波序列下呈均匀信号，FIESTA 序列下信号更不均匀。此外，还可以区分乳头层和网状真皮之间的界面。两种序列和所有部位都可以观察到皮下组织，背部和小腿处的真皮内皮下组织更为明显。最后，FIESTA 序列可以更清晰地显示毛囊和网状真皮的深部血管网络。对根据部位、性别和 MRI 序列的整体皮肤厚度和各层厚度进行了测量。然后进行统计学分析，以根据这些参数寻找结果之间的显著差异。
磁共振成像提供了对各皮肤层（包括皮下组织和肌肉筋膜）的高分辨率的整体分析。
