Volkov O N, Kanaev S V, Stoliarov V I, Malinin A P, Savel'eva O P
Khirurgiia (Mosk). 1991 Apr(4):25-8.
The postradiation changes in carcinoma of the proximal part of the stomach were studied in 32 patients: the parenchymal volume (PV), the damage index (DI), and the mitotic index (MI). The controls were 15 cases in which radiotherapy was not applied. Radiotherapy with large fractions (5 Gy 4 times daily) reduced the PV to 27 +/- 0.8 u on average as compared to the controls (77 +/- 1 u) and lowered the MI to 2.3 +/- 0.5% as compared to the controls (8% +/- 1), the DI ranged widely (3-67%). The methods of quantitative morphological study of tumors may be useful in objective evaluation of the efficacy of various schemes of preoperative concentrated irradiation.
对32例胃近端癌患者放疗后的变化进行了研究，包括实质体积（PV）、损伤指数（DI）和有丝分裂指数（MI）。对照组为15例未接受放疗的患者。大分割放疗（每日4次，每次5 Gy）使PV平均降至27±0.8 u，而对照组为77±1 u；MI降至2.3±0.5%，而对照组为8%±1%，DI范围较广（3 - 67%）。肿瘤定量形态学研究方法可能有助于客观评估术前集中照射各种方案的疗效。
