Talaev M I, Starinskiĭ V V, Kovalev B N, Sidorova E A, Popova A A, Mavrodi V M, Kremlev V V, Laletin V G, Tret'iakov I V
Vopr Onkol. 1990;36(12):1485-8.
The paper discusses the results of a cooperative study concerned with the immediate and end results of treatment of stage III cancer of the antral part and body of the stomach in patients randomly assigned to receive surgery either alone (142 cases) or in combination with preoperative Co 60 gamma teletherapy (139). Preoperative radiotherapy was not followed by increase in postoperative complication rate as compared to surgery alone. Combined treatment appeared to assure higher three- and five-year survival. Irradiation in the total dose of 20 Gy induced grade I-II pathomorphosis of tumor. Ways towards raising the efficacy of the radiation component of combined (radiosurgical) treatment of gastric cancer need to be further investigated.
本文讨论了一项合作研究的结果,该研究涉及随机分配接受单纯手术(142例)或联合术前钴60伽马远距离治疗(139例)的胃窦部和胃体部III期癌症患者的近期和最终治疗结果。与单纯手术相比,术前放疗并未导致术后并发症发生率增加。联合治疗似乎能确保更高的三年和五年生存率。20Gy的总剂量照射导致肿瘤出现I-II级病理形态改变。提高胃癌联合(放射外科)治疗中放射部分疗效的方法有待进一步研究。