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一名患有遗传性出血性毛细血管扩张症的患者,因腹腔内病灶引发了未被察觉的多微生物性脑脓肿。

Unsuspected polymicrobial brain abscess arising from an intra-abdominal source in a patient with hereditary hemorrhagic telangiectasia.

作者信息

Diaz Melina, Cuellar Jose, Valencia-Rey Paula A, Fisher John F

机构信息

Section of Infectious Diseases, Medical College of Georgia, Augusta, GA 30912-3130, USA.

出版信息

South Med J. 2010 Aug;103(8):842-4. doi: 10.1097/SMJ.0b013e3181e6d16e.

DOI:10.1097/SMJ.0b013e3181e6d16e
PMID:20622729
Abstract

The unusual and unprecedented occurrence of a patient with hereditary hemorrhagic telangiectasia (HHT) and a polymicrobial abscess with three different organisms, including fungi, is reported. The patient was a 48-year-old woman with human immunodeficiency virus (HIV) infection and HHT who was brought to the hospital after a motor vehicle accident with altered mental status. Computed tomography did not reveal evidence of acute brain injury but showed a left frontal brain abscess. The patient underwent neurosurgical drainage of the abscess. On culture the abscess yielded methicillin-resistant Staphylococcus aureus, Streptococcus intermedius, and Candida guilliermondii.

摘要

据报道,一名患有遗传性出血性毛细血管扩张症(HHT)的患者出现了罕见且前所未有的情况,即患有由三种不同生物体(包括真菌)引起的多种微生物脓肿。该患者是一名48岁感染人类免疫缺陷病毒(HIV)且患有HHT的女性,在一次机动车事故后因精神状态改变被送往医院。计算机断层扫描未发现急性脑损伤的证据,但显示左额叶脑脓肿。患者接受了脓肿的神经外科引流。脓肿培养结果显示为耐甲氧西林金黄色葡萄球菌、中间链球菌和季也蒙念珠菌。

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Unsuspected polymicrobial brain abscess arising from an intra-abdominal source in a patient with hereditary hemorrhagic telangiectasia.一名患有遗传性出血性毛细血管扩张症的患者,因腹腔内病灶引发了未被察觉的多微生物性脑脓肿。
South Med J. 2010 Aug;103(8):842-4. doi: 10.1097/SMJ.0b013e3181e6d16e.
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A brain abscess following dental extractions in a patient with hereditary hemorrhagic telangiectasia.
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Cerebral abscesses in hereditary haemorrhagic telangiectasia: a clinical and microbiological evaluation.遗传性出血性毛细血管扩张症中的脑脓肿:一项临床和微生物学评估。
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[Familial brain abscess as a complication of hereditary hemorrhagic telangiectasia].
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Recurrent brain abscesses in an HIV-positive patient with hereditary hemorrhagic telangiectasia and arteriovenous malformations of the lung.一名患有遗传性出血性毛细血管扩张症和肺动静脉畸形的HIV阳性患者出现复发性脑脓肿。
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Brain abscess in patients with hereditary hemorrhagic telangiectasia: case report and literature review.遗传性出血性毛细血管扩张症患者的脑脓肿:病例报告及文献综述
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[Osler-Weber-Rendu syndrome: increased risk of infections and life-threatening complications. Four cases of invasive infectious disease over the same period described].[遗传性出血性毛细血管扩张症:感染风险增加及危及生命的并发症。同期描述的4例侵袭性感染性疾病]
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