Thurnheer R, Vernazza P L, Galeazzi R L
Department of Medicine, Kantonsspital St. Gallen, Switzerland.
Eur J Clin Microbiol Infect Dis. 1996 May;15(5):407-10. doi: 10.1007/BF01690100.
Patients with hereditary hemorrhagic telangiectasia are at risk for the development of brain abscesses. The history of a 47-year-old man infected with the human immunodeficiency virus and with hereditary hemorrhagic telangiectasia is reported. Within eight months, the patient presented twice with life-threatening cerebral abscesses at different sites. On both occasions, Streptococcus anginosus was cultured from the abscess material. Treatment consisted of parenteral antibiotics and neurosurgical drainage. After treatment of the second occurrence, the patient was placed on a prophylactic regimen of clindamycin. He remains relapse-free and is clinically stable 24 months after the second episode.
遗传性出血性毛细血管扩张症患者有发生脑脓肿的风险。本文报告了一名47岁感染人类免疫缺陷病毒且患有遗传性出血性毛细血管扩张症男性的病史。在八个月内，该患者两次出现不同部位危及生命的脑脓肿。两次脓肿引流物培养均发现咽峡炎链球菌。治疗包括胃肠外使用抗生素和神经外科引流。第二次发作治疗后，患者接受了克林霉素预防性治疗。第二次发作后24个月，他未再复发，临床状况稳定。
