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[年龄相关性不孕的治疗选择]

[Treatment options for age-related infertility].

作者信息

Belaisch-Allart Joëlle

机构信息

Service de gynécologie obstétrique et médecine de la reproduction, Centre hospitalier des Quatre Villes, site de Sèvres, 92318 Sèvres Cedex.

出版信息

Rev Prat. 2010 Jun 20;60(6):819-23.

Abstract

There has been a consistent trend towards delayed childbearing in most Western countries. Treatment options for age-related infertility includes controlled ovarian hyperstimulation with intrauterine insemination and in vitro fertilization (IVF). A sharp decline in pregnancy rate with advancing female age is noted with assisted reproductive technologies (ART) including IVF. Evaluation and treatment of infertility should not be delayed in women 35 years and older. No treatment other than oocyte donation has been shown to be effective for women over 40 and for those with compromised ovarian reserve, but its pratice is not easy in France hence the procreative tourism. As an increasing number of couples choose to postpone childbearing, they should be informed that maternal age is an important risk factor for failure to conceive.

摘要

在大多数西方国家,晚育的趋势一直存在。与年龄相关的不孕症的治疗选择包括控制性卵巢过度刺激联合宫内人工授精和体外受精(IVF)。包括IVF在内的辅助生殖技术(ART)显示,随着女性年龄的增长,妊娠率会急剧下降。对于35岁及以上的女性,不孕症的评估和治疗不应延迟。除了卵母细胞捐赠外,没有其他治疗方法被证明对40岁以上以及卵巢储备功能受损的女性有效,但在法国实施起来并不容易,因此出现了生育旅游。随着越来越多的夫妇选择推迟生育,应该告知他们,母亲年龄是受孕失败的一个重要风险因素。

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