Vakhrushev Ia M, Khokhlacheva N A
Eksp Klin Gastroenterol. 2010(4):105-8.
We spent the complex investigation of therapeutic efectiveness of ursosan and afobasol in 125 patients with gallstone disease on early stage (before stones). After the course of treatment we revealed positive changes of clinical symptoms and improvement of biochemical bile compound. Besides we found the positive changes in hormone levels correlated with decreasing of bile lithogenity.
我们对125例早期（结石形成前）胆结石病患者使用熊去氧胆酸和阿福巴索进行了复杂的治疗效果研究。治疗疗程结束后，我们发现临床症状有积极变化，生化胆汁成分有所改善。此外，我们还发现激素水平有积极变化，且与胆汁致石性降低相关。
