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对接种了几种禽腺病毒分离株的鸡进行的临床评估。

A clinical evaluation of chickens inoculated with several avian adenovirus isolants.

作者信息

Henry N W, Rosenberger J K, Lee K P

出版信息

Avian Dis. 1978 Jan-Mar;22(1):46-52.

PMID:206253
Abstract

Clinical-chemistry values were determined in young specific-pathogen-free single-comb White Leghorn chickens, both uninoculated and inoculated intra-abdominally at one day old with one of several avian adenovirus isolants. Clinical values for plasma proteins and enzymes indicative of liver function were determined at 3, 7, 10, 14, and 21 days postinoculation. Plasma glutamic oxalacetic transaminase and glutamic pyruvic transaminase activities were elevated in the virus-inoculated birds, along with decreased albumin levels suggesting liver necrosis, Subsequent histopathologic evaluations confirmed hepatic necrosis in the virus-inoculated groups, demonstrating the potential value of clinical-chemistry assay techniques for diagnosing subclinical disease associated with avian adenoviruses.

摘要

在年轻的无特定病原体单冠白来航鸡中测定临床化学值,这些鸡未接种疫苗,或在一日龄时经腹腔接种几种禽腺病毒分离株之一。在接种后3、7、10、14和21天测定指示肝功能的血浆蛋白和酶的临床值。接种病毒的鸡血浆谷草转氨酶和谷丙转氨酶活性升高,同时白蛋白水平降低,提示肝坏死。随后的组织病理学评估证实接种病毒组存在肝坏死,证明临床化学检测技术在诊断与禽腺病毒相关的亚临床疾病方面的潜在价值。

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