Kuhnert C, Zeca E, Fischer J, Canuet M, Noël E, Rondeau-Lutz M, Weber J-C
Service de médecine interne A, Nouvel hôpital civil, hôpitaux universitaires de Strasbourg, 67091 Strasbourg cedex, France.
Rev Med Interne. 2010 Oct;31(10):e6-8. doi: 10.1016/j.revmed.2009.11.014. Epub 2010 Jun 2.
We report a 46-year-old woman with a metastatic breast cancer who developed a subacute pulmonary hypertension. The final diagnosis was microscopic pulmonary neoplastic emboli. She presented with the typical clinical picture of a pulmonary hypertension with a normal pulmonary angiographic computer tomography and multiple sub-segmental perfusion defects on radionuclide imaging. This serious condition must be known by physicians, because of an opportunity to obtain the diagnosis by the cytologic analysis of sampled microvascular blood obtained with a pulmonary artery catheterization. The prognosis is poor and there is no efficient therapy.
我们报告了一名46岁患有转移性乳腺癌的女性,她出现了亚急性肺动脉高压。最终诊断为显微镜下肺肿瘤栓塞。她表现出肺动脉高压的典型临床症状,肺动脉造影计算机断层扫描正常,但放射性核素成像显示有多个亚段灌注缺损。由于有可能通过肺动脉导管插入术获取的微血管血样进行细胞学分析来确诊,医生必须了解这种严重情况。其预后较差,且没有有效的治疗方法。