Ajibade Dare V, Tanaka Iwao K, Paghdal Kapila V, Mirani Neena, Lee Huey-Jen, Jyung Robert W
Division of Otolaryngology, Department of Surgery, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA.
Ear Nose Throat J. 2010 Jul;89(7):E1-13. doi: 10.1177/014556131008900701.
We report the case of a 41-year-old man who presented with progressive right-sided ear pressure, otalgia, hearing loss, tinnitus, and intermittent otorrhea. Computed tomography and magnetic resonance imaging detected a soft-tissue mass in the right mastoid with intracranial invasion and erosion through the tegmen tympani and mastoid cortex. Histopathologic examination was consistent with an inflammatory pseudotumor (plasma cell granuloma). These lesions rarely occur in the temporal bone. When they do, they are locally destructive and can erode bone and soft tissues. Aggressive surgery is recommended as a first-line treatment, with adjunctive steroid or radiotherapy reserved for residual or refractory disease. Our patient subsequently experienced multiple recurrences, and his treatment required all of these modalities. At the most recent follow-up, he was disease-free and doing well.
我们报告了一例41岁男性患者，其表现为进行性右侧耳部闷胀感、耳痛、听力损失、耳鸣和间歇性耳漏。计算机断层扫描和磁共振成像检测到右侧乳突有一软组织肿块，并通过鼓室盖和乳突皮质向颅内侵犯和侵蚀。组织病理学检查结果符合炎性假瘤（浆细胞性肉芽肿）。这些病变很少发生在颞骨。一旦发生，它们具有局部破坏性，可侵蚀骨质和软组织。建议积极手术作为一线治疗方法，辅助性类固醇或放疗则用于残留或难治性疾病。我们的患者随后经历了多次复发，其治疗需要所有这些方式。在最近的随访中，他无疾病且状况良好。
