D'Orazio Flavia, Falcioni Maurizio, Waskiewicz Justyna, Tredici Manuel, Khoury Charbel, Mancini Cristina
Department of ENT Maxillofacial Surgery, Azienda Sanitaria dell'Alto Adige, 'F. Tappeiner' Hospital, Merano, Italy.
Maurizio Falcioni, Responsabile SSD di Otoneurochirurgia e Microchirurgia della base cranica laterale, AOU di Parma, Italy.
J Int Adv Otol. 2025 Jul 28;21(4):1-6. doi: 10.5152/iao.2025.241790.
We present the case of a 42-year-old female who experienced gradually worsening pain in the left ear, accompanied by hearing impairment and occasional ear discharge. These lesions rarely occur in the temporal bone. Computed tomography and magnetic resonance scans identified a mass of soft tissue located in the left mastoid, with intracranial invasion and mastoid erosion. Initial treatment involved surgery followed by histo- pathology, which confirmed the diagnosis of a plasma cell granuloma, also known as an inflammatory pseudotumor. After surgery, the pseudo- tumor invaded the ipsilateral parapharyngeal space and became surgically inaccessible. Steroid therapy and radiotherapy were proceeded with. When feasible, aggressive surgical intervention is advised as the primary treatment, supplemented by steroids and radiation therapy for persis- tent or recurrent conditions. At the last follow-up, the patient was not completely free of disease but symptom-free and in good general health.
我们报告一例42岁女性病例，该患者左耳疼痛逐渐加重，伴有听力障碍和偶尔的耳漏。这些病变很少发生在颞骨。计算机断层扫描和磁共振扫描发现左乳突有一软组织肿块，伴有颅内侵犯和乳突侵蚀。初始治疗包括手术，随后进行组织病理学检查，确诊为浆细胞肉芽肿，也称为炎性假瘤。手术后，假瘤侵犯同侧咽旁间隙，无法进行手术切除。于是进行了类固醇治疗和放射治疗。可行时，建议积极的手术干预作为主要治疗方法，对于持续或复发情况辅以类固醇和放射治疗。在最后一次随访时，患者疾病未完全消除，但无症状，总体健康状况良好。
