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两例因非结核分枝杆菌感染导致的孤立性肺结节,在正电子发射断层扫描(PET)上呈现出强烈的 18F-氟脱氧葡萄糖摄取。

Two cases with solitary pulmonary nodule due to non-tuberculous mycobacterial infection showing intense 18F-fluorodeoxyglucose uptake on positron emission tomography scan.

机构信息

Division of Respiratory Medicine, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan.

出版信息

Geriatr Gerontol Int. 2010 Jul;10(3):251-4. doi: 10.1111/j.1447-0594.2010.00619.x.

DOI:10.1111/j.1447-0594.2010.00619.x
PMID:20629758
Abstract

We report an 81-year-old man and a 65-year-old woman with a solitary pulmonary nodule (SPN) due to infection with non-tuberculous mycobacteria (NTM). In each case, the nodule showed a high (18)F-fluorodeoxyglucose (FDG) uptake with the maximum standardized uptake values (SUV) of 13.2 and 4.8 on positron emission tomography (PET) imaging, respectively. Both cases required partial lung resection for confirmation of the histological diagnosis. A review of six reported patients with SPN due to NTM infections showed that the SUV of FDG was more than 4.0 in the nodules of all cases. Positive results on FDG-PET should be interpreted cautiously when evaluating SPN, especially in patients having predisposing factors for NTM infections.

摘要

我们报告了一例 81 岁男性和一例 65 岁女性,他们均因感染非结核分枝杆菌(NTM)而患有孤立性肺结节(SPN)。在每种情况下,结节在正电子发射断层扫描(PET)成像上的最高(18)F-氟脱氧葡萄糖(FDG)摄取量均较高,SUV 值分别为 13.2 和 4.8。这两种情况均需要进行部分肺切除术以确认组织学诊断。对六例因 NTM 感染而导致 SPN 的报道病例进行回顾,结果显示所有病例的结节 FDG 的 SUV 均大于 4.0。在评估 SPN 时,尤其是在有 NTM 感染易感因素的患者中,应谨慎解读 FDG-PET 的阳性结果。

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