Sureyyapasa Chest Diseases and Thoracic Surgery Training and Investigation Hospital, Department of Pediatric Pulmonology, Istanbul, Turkey.
Pediatr Pulmonol. 2010 Oct;45(10):1040-2. doi: 10.1002/ppul.21299.
Chronic eosinophilic pneumonia is a rare cause of chronic lung disease in children. A 7-year-old girl who attended our clinics with cough and sputum lasting for 5 years, has been evaluated for bilateral alveolar infiltration and ground-glass opacities. Peripheral eosinophilia was detected in total cell blood count. Flexible bronchoscopy showed mucous plugs. Bronchoalveolar lavage fluid and cell block of mucous plugs determined hypereosinophilia. Chronic eosinophilic pneumonia was confirmed after the elimination of other eosinophilic lung diseases and the case was accepted to be idiopathic. She showed a dramatic response to oral corticosteroids. This is the first reported case of chronic eosinophilic pneumonia presenting with mucous plugs in children described to date in the literature.
慢性嗜酸性粒细胞性肺炎是儿童慢性肺部疾病的一种罕见病因。一名 7 岁女孩因咳嗽和咳痰持续 5 年就诊于我院,胸部影像学检查提示双肺肺泡浸润和磨玻璃影。全血细胞计数显示外周血嗜酸性粒细胞增多。纤维支气管镜检查发现黏液栓。支气管肺泡灌洗液和黏液栓的细胞块检查提示嗜酸性粒细胞增多。在排除其他嗜酸性肺病后,确诊为慢性嗜酸性粒细胞性肺炎,该病例为特发性。她对口服皮质类固醇反应良好。这是迄今为止文献中首例报道的儿童以黏液栓为表现的慢性嗜酸性粒细胞性肺炎病例。