生长激素促分泌素：不仅仅是内源性生长激素促分泌素。
Ghrelin: more than endogenous growth hormone secretagogue.
机构信息
Molecular Genetics, Institute of Life Science, Kurume University, Kurume, Fukuoka, Japan.
出版信息
Ann N Y Acad Sci. 2010 Jul;1200:140-8. doi: 10.1111/j.1749-6632.2010.05516.x.
Since its discovery 10 years ago, intensive research has been performed on ghrelin. The significance of ghrelin as a growth hormone-releasing hormone, appetite regulator, energy conservator, and sympathetic nerve suppressor has now been well established. In this review, we summarize recent topics on ghrelin, such as the processing protease of the ghrelin precursor, ghrelin O-acyl transaferase, ghrelin knockout and transgenic mice, and the molecular mechanism of ghrelin's orexigenesis.
自 10 年前发现以来，人们对 ghrelin 进行了大量研究。ghrelin 作为生长激素释放激素、食欲调节剂、能量储存器和交感神经抑制剂的意义现在已经得到很好的确立。在这篇综述中，我们总结了 ghrelin 的最新研究课题，如 ghrelin 前体的加工蛋白酶、ghrelin O-酰基转移酶、ghrelin 敲除和转基因小鼠，以及 ghrelin 促食欲作用的分子机制。
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