丹麦的脐膨出双胞胎（1970-1989）。

Twins with omphalocele in Denmark (1970-1989).

机构信息

Wilhelm Johannsen Centre for Functional Genome Research, Department of Cellular and Molecular Medicine, Panum Institute, University of Copenhagen, Copenhagen, Denmark.

出版信息

Am J Med Genet A. 2010 Aug;152A(8):2048-52. doi: 10.1002/ajmg.a.33494.

DOI:10.1002/ajmg.a.33494

PMID:20635337

Abstract

Seven pairs of twins, two monozygotic (MZ), two dizygotic (DZ), and three like-sex pairs of unknown zygosity are described. The twin pairs were all discordant for omphalocele except for one pair of conjoined twins. The 8 infants with omphalocele represent 3.1% of the 253 infants with omphalocele, ascertained in an almost complete nationwide data set of live- and stillborn infants with abdominal wall defects in two decades in Denmark (1970-1989). The occurrence of twins with omphalocele was not significantly different from the occurrence of twins in the Danish population in the same period. To our knowledge this is the first report of the occurrence of twins with omphalocele in a systematic nationwide epidemiological study.

摘要

本文报道了 7 对双胞胎，其中 2 对为单卵双胎（MZ），2 对为双卵双胎（DZ），3 对为同性别且来源不明的双胎。除了一对联体双胎外，其余的双胎均为脐膨出不一致。8 例脐膨出患儿占 253 例脐膨出活产和死产患儿（1970-1989 年丹麦近 20 年全国性腹壁缺陷患儿登记资料）的 3.1%。脐膨出患儿中双胎的发生率与同期丹麦人群中双胎的发生率无显著差异。据我们所知，这是首次在系统的全国性流行病学研究中报道脐膨出双胎的发生情况。