Razumov V V, Bondarev O I
Med Tr Prom Ekol. 2010(5):31-6.
Morphometric studies covered lung tissue of 10 miners exposed to dusty work conditions over 1 to 30 (13.4 +/- 3.6) years, who were considered apparently healthy according to follow-up examinations and died in technogenic accident. Findings are that dysregeneration, hypertrophic and sclerotic changes in respiratory part of lungs, in bronchi and in pulmonary circuit arteries develop simultaneously--that proves common pathogenetic concept of these changes and systemic character of the pneumoconiosis. The results necessitate improved methods to evaluate health state of workers, refined criteria for nosologic diagnosis of respiratory diseases related to dust.
形态计量学研究涵盖了10名矿工的肺组织，这些矿工在有粉尘的工作环境中暴露了1至30年（13.4±3.6年），根据随访检查，他们被认为表面健康，后死于技术事故。研究结果表明，肺部呼吸部分、支气管和肺循环动脉的再生失调、肥大和硬化变化同时出现，这证明了这些变化的共同发病机制概念以及尘肺病的系统性特征。这些结果需要改进评估工人健康状况的方法，完善与粉尘相关的呼吸系统疾病的疾病诊断标准。
