Departmento de Patologia Clínica, Faculdade de Veterinária, UFRGS. Porto Alegre-RS, Brazil.
Equine Vet J. 2010 Jul;42(5):456-9. doi: 10.1111/j.2042-3306.2010.00035.x.
After ingesting green leaves of T. micrantha, 2 horses showed apathy, locomotor deficit, blindness, recumbency, paddling, coma and death. The main gross findings were scattered haemorrhages, enhanced lobular pattern of the liver, and cerebral oedema. Histological changes included disseminated haemorrhages, massive hepatocellular necrosis, neuronal degeneration, Alzheimer type II astrocytes and cerebral perivascular oedema. Clinicopathological findings which were comparable with those observed in Trema micrantha poisoned ruminants, associated with epidemiological evidence suggested the diagnosis.Trema micrantha poisoning should be evaluated as a possible cause in the diagnosis of equine hepatopathy and occasional secondary encephalopathy.
进食三叶鬼针草的绿色叶子后，2 匹马表现出冷漠、运动缺陷、失明、卧倒、划水、昏迷和死亡。主要的大体发现是散在性出血、肝脏小叶模式增强，以及脑水肿。组织学变化包括弥散性出血、大量肝细胞坏死、神经元变性、阿尔茨海默病 II 型星形胶质细胞和脑血管周围水肿。与三叶鬼针草中毒反刍动物观察到的临床病理发现相类似，结合流行病学证据提示了该诊断。三叶鬼针草中毒应作为马肝病和偶发性继发性脑病的可能病因进行评估。
