Suemaru S, Kageyama J, Ota Z, Ohnoshi T, Sakamoto K, Kamura J
Third Department of Internal Medicine, Okayama University Medical School, Japan.
Acta Med Okayama. 1991 Feb;45(1):55-9. doi: 10.18926/AMO/32221.
A patient with a diffuse, small cleaved cell, non-Hodgkin's lymphoma associated with marked hypecalcemia was described. Antibody to the adult T-cell leukemia-lymphoma virus was absent. Although bone marrow was infiltrated by lymphoma cells, destructive or lytic bone lesions could not be detected. The serum level of immunoreactive parathyroid hormone C-terminal (PTH-C) was normal. The serum level of 1, 25-dihydroxyvitamin D was lower than normal. This case suggests that other humoral substances produced by lymphoma cells may be responsible for hypercalcemia.
描述了一名患有弥漫性小裂细胞非霍奇金淋巴瘤并伴有明显高钙血症的患者。未检测到抗成人T细胞白血病-淋巴瘤病毒抗体。尽管骨髓被淋巴瘤细胞浸润，但未检测到破坏性或溶骨性骨病变。免疫反应性甲状旁腺激素C末端（PTH-C）的血清水平正常。1,25-二羟维生素D的血清水平低于正常。该病例提示淋巴瘤细胞产生的其他体液物质可能是高钙血症的原因。
