University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
Nephron Clin Pract. 2010;116(4):c269-73. doi: 10.1159/000318788. Epub 2010 Jul 16.
High blood pressure in South Africa is estimated to have caused 46,888 deaths and 390,860 disability-adjusted life years in 2000. Detection and management of hypertension remains suboptimal due to inadequate public health care facilities. Mass migration of rural blacks to urban areas and rapid changes in lifestyle and risk factors account for the rising prevalence of hypertension, but genetic factors may also play an important contributory role. Black South Africans also appear to be more prone to complications of hypertension, particularly stroke, heart failure, and hypertensive nephrosclerosis, and respond poorly to ACE inhibitors as monotherapy. Proactive public health interventions at a population level need to be introduced to control this growing epidemic.
2000 年,南非的高血压估计导致了 46888 人死亡和 390860 个伤残调整生命年。由于公共卫生保健设施不足,高血压的检测和管理仍然不理想。农村黑人大量迁移到城市地区以及生活方式和危险因素的迅速变化导致高血压的患病率上升,但遗传因素也可能起重要的促成作用。南非黑人似乎也更容易出现高血压并发症,特别是中风、心力衰竭和高血压性肾硬化,并且对 ACE 抑制剂单药治疗反应不佳。需要在人群层面上采取积极的公共卫生干预措施来控制这一不断增长的流行。