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[老年人的多重用药与跌倒]

[Polypharmacy and falls in the Elderly].

作者信息

Sommeregger Ulrike, Iglseder Bernhard, Böhmdorfer Birgit, Benvenuti-Falger Ursula, Dovjak Peter, Lechleitner Monika, Otto Ronald, Roller Regina E, Gosch Markus

机构信息

Abteilung für Akutgeriatrie, Krankenhaus Hietzing mit Neurologischem Zentrum Rosenhügel, Wien, Austria.

Universitätsklinik für Geriatrie, Paracelsus Medizinische Privatuniversität, Salzburg, Austria.

出版信息

Wien Med Wochenschr. 2010 Jun;160(11-12):293-296. doi: 10.1007/s10354-010-0789-y.

DOI:10.1007/s10354-010-0789-y
PMID:20640927
Abstract

Falls and their consequences are a major problem in geriatric medicine. Main causes are the combination of age-related physiological changes with multimorbidity and subsequent polypharmacy. Elderly patients are more susceptible to adverse drug effects and have less compensatory capacity than younger adults. Therefore careful monitoring of side effects is indicated and prescribing for elderly patients calls for alertness in order to identify symptoms as possible adverse drug effects.

摘要

跌倒及其后果是老年医学中的一个主要问题。主要原因是与年龄相关的生理变化、多种疾病并存以及随后的多种药物治疗。老年患者比年轻人更容易受到药物不良反应的影响,且代偿能力更弱。因此,需要仔细监测副作用,为老年患者开处方时需要保持警惕,以便将症状识别为可能的药物不良反应。

相似文献

1
[Polypharmacy and falls in the Elderly].[老年人的多重用药与跌倒]
Wien Med Wochenschr. 2010 Jun;160(11-12):293-296. doi: 10.1007/s10354-010-0789-y.
2
Revisiting medication use in a frail 93-year-old man experiencing possible adverse effects.重新审视一位93岁体弱男性可能出现不良反应的用药情况。
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Eur J Clin Pharmacol. 2013 Mar;69(3):319-26. doi: 10.1007/s00228-012-1387-2. Epub 2012 Sep 11.
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[Drug treatment of elderly patients].
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Adverse drug reactions in special populations - the elderly.特殊人群中的药物不良反应——老年人
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Australian and New Zealand Society for Geriatric Medicine: position statement - frailty in older people.澳大利亚和新西兰老年医学协会:立场声明——老年人的衰弱问题
Australas J Ageing. 2015 Mar;34(1):68-73. doi: 10.1111/ajag.12195.
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Family conferences and shared prioritisation to improve patient safety in the frail elderly (COFRAIL): study protocol of a cluster randomised intervention trial in primary care.家庭会议和共同优先级排序以改善虚弱老年人的患者安全(COFRAIL):初级保健中群组随机干预试验的研究方案。
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Incidence and Effects of Polypharmacy on Clinical Outcome among Patients Aged 80+: A Five-Year Follow-Up Study.80岁及以上患者多重用药的发生率及其对临床结局的影响:一项五年随访研究
PLoS One. 2015 Nov 10;10(11):e0142123. doi: 10.1371/journal.pone.0142123. eCollection 2015.
9
Polypharmacy and inappropriate prescribing in elderly internal-medicine patients in Austria.奥地利老年内科患者的多重用药与不适当处方
Wien Klin Wochenschr. 2008;120(23-24):733-41. doi: 10.1007/s00508-008-1089-z.
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引用本文的文献

1
Tools in polypharmacy. Current evidence from observational and controlled studies.多重用药的工具。观察性研究和对照研究的当前证据。
Z Gerontol Geriatr. 2012 Aug;45(6):468-72. doi: 10.1007/s00391-012-0362-y.

本文引用的文献

1
Inappropriate medication use and risk of falls--a prospective study in a large community-dwelling elderly cohort.不适当的药物使用与跌倒风险——一项针对大型社区居住老年队列的前瞻性研究。
BMC Geriatr. 2009 Jul 23;9:30. doi: 10.1186/1471-2318-9-30.
2
Number and dosage of central nervous system medications on recurrent falls in community elders: the Health, Aging and Body Composition study.社区老年人复发性跌倒时中枢神经系统药物的数量和剂量:健康、衰老与身体成分研究
J Gerontol A Biol Sci Med Sci. 2009 Apr;64(4):492-8. doi: 10.1093/gerona/gln043. Epub 2009 Feb 4.
3
Polypharmacy and inappropriate prescribing in elderly internal-medicine patients in Austria.
奥地利老年内科患者的多重用药与不适当处方
Wien Klin Wochenschr. 2008;120(23-24):733-41. doi: 10.1007/s00508-008-1089-z.
4
Poor vision accompanied with other sensory impairments as a predictor of falls in older women.视力不佳伴有其他感官障碍作为老年女性跌倒的预测因素。
Age Ageing. 2009 Mar;38(2):162-7. doi: 10.1093/ageing/afn228. Epub 2008 Nov 13.
5
Lowered vision as a risk factor for injurious accidents in older people.视力下降作为老年人发生伤害性事故的一个风险因素。
Aging Clin Exp Res. 2008 Feb;20(1):25-30. doi: 10.1007/BF03324744.
6
Effectiveness of falls clinics: an evaluation of outcomes and client adherence to recommended interventions.跌倒诊所的有效性:对结果及患者对推荐干预措施的依从性的评估。
J Am Geriatr Soc. 2008 Apr;56(4):600-8. doi: 10.1111/j.1532-5415.2007.01626.x. Epub 2008 Feb 7.
7
Falls in the community-dwelling older adult: a review for primary-care providers.社区居住老年人的跌倒:给初级保健提供者的综述
Clin Interv Aging. 2007;2(4):545-54. doi: 10.2147/cia.s1080.
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[Post-fall syndrome: how to recognize and treat it?].
Rev Med Suisse. 2007 Nov 7;3(132):2531-2, 2534, 2536.
9
Withdrawal of fall-risk-increasing drugs in older persons: effect on mobility test outcomes.老年人停用增加跌倒风险药物:对运动测试结果的影响。
Drugs Aging. 2007;24(8):691-9. doi: 10.2165/00002512-200724080-00006.
10
Recurrent hyponatremia associated with citalopram and mirtazapine.与西酞普兰和米氮平相关的复发性低钠血症。
Am J Kidney Dis. 2006 Oct;48(4):e61-2. doi: 10.1053/j.ajkd.2006.07.011.