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运动疗法在实体瘤治疗中的应用。

Exercise therapy in the management of solid tumors.

机构信息

Duke University Medical Center, Box 3085, Durham, NC 27710, USA,

出版信息

Curr Treat Options Oncol. 2010 Jun;11(1-2):45-58. doi: 10.1007/s11864-010-0121-5.

DOI:10.1007/s11864-010-0121-5
PMID:20645033
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3619217/
Abstract

OPThe benefits of exercise in patients with chronic disease have been studied extensively over the last half century. In contrast, investigation of the role of exercise following a diagnosis of cancer has received comparably less attention. In this article, we review the efficacy of exercise training in specific areas across the cancer survivorship continuum [i.e., pre-surgery, post-surgery during adjuvant therapy, following the completion of primary adjuvant therapy (survivorship), and palliation], with a view toward future research. The current evidence base provides strong but preliminary evidence that exercise training is a well-tolerated and safe adjunct therapy that can mitigate several common treatment-related side-effects among cancer patients with early disease both during and following adjuvant therapy although many questions remain unanswered. Preliminary evidence in this area supports that exercise therapy may be an important consideration in multidisciplinary management of patients following a cancer diagnosis.

摘要

在过去的半个世纪里,人们对慢性疾病患者运动的益处进行了广泛的研究。相比之下,对于癌症诊断后运动的作用的研究则相对较少。在本文中,我们回顾了运动训练在癌症生存者连续体的特定领域中的疗效[即在手术前、辅助治疗期间的手术后、完成主要辅助治疗后(生存阶段)和姑息治疗期间],以期展望未来的研究。目前的证据基础提供了强有力但初步的证据,表明运动训练是一种耐受良好且安全的辅助治疗方法,可减轻早期疾病癌症患者在辅助治疗期间和之后治疗相关的几种常见副作用,尽管仍有许多问题尚未得到解答。这一领域的初步证据支持,运动疗法可能是癌症诊断后患者多学科管理的一个重要考虑因素。

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Exercise therapy in the management of solid tumors.运动疗法在实体瘤治疗中的应用。
Curr Treat Options Oncol. 2010 Jun;11(1-2):45-58. doi: 10.1007/s11864-010-0121-5.
2
Erratum to: Exercise therapy in the management of solid tumors.勘误:运动疗法在实体瘤治疗中的应用。
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Running away from side effects: physical exercise as a complementary intervention for breast cancer patients.逃离副作用:体育锻炼作为乳腺癌患者的辅助干预措施
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本文引用的文献

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Exercise ventilatory inefficiency and mortality in patients with chronic obstructive pulmonary disease undergoing surgery for non-small-cell lung cancer.运动通气效率不足与非小细胞肺癌手术患者的慢性阻塞性肺疾病死亡率相关。
Eur J Cardiothorac Surg. 2010 Jul;38(1):14-9. doi: 10.1016/j.ejcts.2010.01.032. Epub 2010 Mar 30.
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The cardiac safety of trastuzumab in the treatment of breast cancer.曲妥珠单抗治疗乳腺癌的心脏安全性。
Expert Opin Drug Saf. 2010 Mar;9(2):335-46. doi: 10.1517/14740331003627441.
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J Cancer Surviv. 2010 Jun;4(2):87-100. doi: 10.1007/s11764-009-0110-5. Epub 2010 Jan 6.
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Voluntary wheel running in rats receiving doxorubicin: effects on running activity and cardiac myosin heavy chain.接受阿霉素治疗的大鼠进行自愿轮跑运动:对跑步活动和心肌肌球蛋白重链的影响。
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Cancer. 2010 Feb 1;116(3):695-704. doi: 10.1002/cncr.24808.