Courneya Kerry S, Rogers Laura Q, Campbell Kristin L, Vallance Jeff K, Friedenreich Christine M
a University of Alberta.
Res Q Exerc Sport. 2015 Jun;86(2):107-16. doi: 10.1080/02701367.2015.991265. Epub 2015 Jan 28.
In the United States, there are more than 14 million cancer survivors. Many of these survivors have been treated with multimodal therapy including surgery, radiation therapy, chemotherapy, and targeted therapies. These therapies improve survival; however, they also cause acute and chronic side effects that can undermine health and quality of life. Physical activity (PA) and cancer survivorship is a rapidly growing field of inquiry that studies the role of PA in people diagnosed with cancer. In this article, we propose the following top 10 research questions for the field of PA and cancer survivorship: (1) Does PA reduce the risk for cancer recurrence and/or improve survival? (2) Does PA influence cancer treatment decisions, completion rates, and/or response? (3) What is the optimal PA prescription for cancer survivors? (4) What is the role of sedentary behavior in cancer survivorship? (5) What are the most effective PA behavior change interventions for cancer survivors? (6) Which cancer variables modify the PA response? (7) What are the safety issues concerning PA in cancer survivors? (8) Which specific cancer symptoms can be managed by PA? (9) Is there a role for PA in advanced cancer? And (10) How do we translate PA research into clinical and community oncology practice? The answers to these questions are critical not only for advancing the field of PA and cancer survivorship, but for improving the lives of the millions of cancer survivors every year who are diagnosed with cancer, going through treatments, recovering after treatments, or coping with advanced disease.
在美国，有超过1400万癌症幸存者。这些幸存者中有许多人接受了包括手术、放疗、化疗和靶向治疗在内的多模式治疗。这些治疗提高了生存率；然而，它们也会导致急性和慢性副作用，可能损害健康和生活质量。身体活动（PA）与癌症 survivorship是一个迅速发展的研究领域，该领域研究PA在被诊断患有癌症的人群中的作用。在本文中，我们针对PA与癌症 survivorship领域提出以下十大研究问题：（1）PA是否能降低癌症复发风险和/或提高生存率？（2）PA是否会影响癌症治疗决策、完成率和/或反应？（3）癌症幸存者的最佳PA处方是什么？（4）久坐行为在癌症 survivorship中的作用是什么？（5）对癌症幸存者最有效的PA行为改变干预措施有哪些？（6）哪些癌症变量会改变PA反应？（7）癌症幸存者进行PA时存在哪些安全问题？（8）PA可以管理哪些特定的癌症症状？（9）PA在晚期癌症中是否有作用？以及（10）我们如何将PA研究转化为临床和社区肿瘤学实践？这些问题的答案不仅对于推进PA与癌症 survivorship领域至关重要，而且对于改善每年数百万被诊断患有癌症、正在接受治疗、治疗后康复或应对晚期疾病的癌症幸存者的生活也至关重要。
