Hong Kong Head and Neck Ear Nose Throat Surgery Centre, Hong Kong, Central Building, Central, Hong Kong.
Head Neck. 2011 Apr;33(4):453-7. doi: 10.1002/hed.21462.
It has been shown that occult thyroid carcinoma can be identified in about 10% of thyroid glands in autopsy. The purpose of this study was to evaluate the prevalence of asymptomatic thyroid carcinoma in the Hong Kong Chinese population by ultrasonographic screening.
Volunteer subjects without symptoms of thyroid disease were recruited for ultrasonographic screening for thyroid cancer. A total of 1140 subjects were recruited in this study.
Thyroid nodules were found in 45% subjects (511 of 1140); the mean age was 48 years. Ultrasonographic-guided aspiration cytology was performed in 258 subjects. Twenty-six subjects (2.3%) had cytologic findings suspicious of malignancy. Fourteen subjects (1.2%) had pathologic diagnosis of thyroid cancer, including 13 papillary carcinomas and 1 follicular carcinoma.
A high incidence of occult thyroid cancer could be identified on ultrasonographic screening. Subjects could benefit with early diagnosis with either early intervention or close monitoring.
尸检显示约 10%的甲状腺中可发现隐匿性甲状腺癌。本研究旨在通过超声筛查评估香港华人无症状甲状腺癌的患病率。
招募无甲状腺疾病症状的志愿者进行甲状腺癌超声筛查。本研究共招募了 1140 名受试者。
45%（511/1140）的受试者发现甲状腺结节；平均年龄为 48 岁。对 258 名受试者进行了超声引导下细针抽吸细胞学检查。26 名（2.3%）受试者的细胞学检查结果疑似恶性。14 名（1.2%）受试者的病理诊断为甲状腺癌，包括 13 例乳头状癌和 1 例滤泡状癌。
超声筛查可发现隐匿性甲状腺癌的高发病率。通过早期诊断，无论是早期干预还是密切监测，患者都将从中获益。
