• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Enantioselectivity of haloalkane dehalogenases and its modulation by surface loop engineering.

作者信息

Prokop Zbynek, Sato Yukari, Brezovsky Jan, Mozga Tomas, Chaloupkova Radka, Koudelakova Tana, Jerabek Petr, Stepankova Veronika, Natsume Ryo, van Leeuwen Jan G E, Janssen Dick B, Florian Jan, Nagata Yuji, Senda Toshiya, Damborsky Jiri

机构信息

Loschmidt Laboratories, Department of Experimental Biology and Centre for Toxic Compounds in the Environment, Faculty of Science, Masaryk University, Kamenice 5/A13, 625 00 Brno, Czech Republic.

出版信息

Angew Chem Int Ed Engl. 2010 Aug 16;49(35):6111-5. doi: 10.1002/anie.201001753.

DOI:10.1002/anie.201001753
PMID:20645368
Abstract
摘要

相似文献

1
Enantioselectivity of haloalkane dehalogenases and its modulation by surface loop engineering.卤代烷脱卤酶的对映选择性及其通过表面环工程的调控。
Angew Chem Int Ed Engl. 2010 Aug 16;49(35):6111-5. doi: 10.1002/anie.201001753.
2
Two rhizobial strains, Mesorhizobium loti MAFF303099 and Bradyrhizobium japonicum USDA110, encode haloalkane dehalogenases with novel structures and substrate specificities.两种根瘤菌菌株，百脉根中生根瘤菌MAFF303099和大豆慢生根瘤菌USDA110，编码具有新颖结构和底物特异性的卤代烷脱卤酶。
Appl Environ Microbiol. 2005 Aug;71(8):4372-9. doi: 10.1128/AEM.71.8.4372-4379.2005.
3
Crystallization and preliminary crystallographic analysis of a haloalkane dehalogenase, DbjA, from Bradyrhizobium japonicum USDA110.来自日本慢生根瘤菌USDA110的卤代烷脱卤酶DbjA的结晶及初步晶体学分析
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Apr 1;63(Pt 4):294-6. doi: 10.1107/S1744309107008652. Epub 2007 Mar 12.
4
Evolving haloalkane dehalogenases.不断进化的卤代烷脱卤酶
Curr Opin Chem Biol. 2004 Apr;8(2):150-9. doi: 10.1016/j.cbpa.2004.02.012.
5
Stereoselectivity and conformational stability of haloalkane dehalogenase DbjA from Bradyrhizobium japonicum USDA110: the effect of pH and temperature.手性选择性和 haloalkane 脱卤酶 DbjA 构象稳定性来自 Bradyrhizobium japonicum USDA110：pH 和温度的影响。
FEBS J. 2011 Aug;278(15):2728-38. doi: 10.1111/j.1742-4658.2011.08203.x. Epub 2011 Jun 27.
6
Cloning, functional expression, biochemical characterization, and structural analysis of a haloalkane dehalogenase from Plesiocystis pacifica SIR-1.太平洋硫杆菌 SIR-1 中卤代烷烃脱卤酶的克隆、功能表达、生化特性和结构分析。
Appl Microbiol Biotechnol. 2011 Aug;91(4):1049-60. doi: 10.1007/s00253-011-3328-x. Epub 2011 May 21.
7
A single point mutation enhances hydroxynitrile synthesis by halohydrin dehalogenase.一个单点突变通过卤代醇脱卤酶增强了羟基腈的合成。
Enzyme Microb Technol. 2015 Mar;70:50-7. doi: 10.1016/j.enzmictec.2014.12.009. Epub 2014 Dec 24.
8
X-ray crystal structure of Mycobacterium tuberculosis haloalkane dehalogenase Rv2579.结核分枝杆菌卤代烷脱卤酶Rv2579的X射线晶体结构。
Biochim Biophys Acta. 2008 Feb;1784(2):351-62. doi: 10.1016/j.bbapap.2007.10.014. Epub 2007 Nov 13.
9
Ancestral Haloalkane Dehalogenases Show Robustness and Unique Substrate Specificity.祖传卤代烷脱卤酶表现出强大的稳定性和独特的底物特异性。
Chembiochem. 2017 Jul 18;18(14):1448-1456. doi: 10.1002/cbic.201700197. Epub 2017 Jun 12.
10
Substrate specificity of haloalkane dehalogenases.卤代烷烃脱卤酶的底物特异性。
Biochem J. 2011 Apr 15;435(2):345-54. doi: 10.1042/BJ20101405.

引用本文的文献

1
Decoding Protein Stabilization: Impact on Aggregation, Solubility, and Unfolding Mechanisms.蛋白质稳定性解码：对聚集、溶解性及解折叠机制的影响
J Chem Inf Model. 2025 Aug 25;65(16):8688-8701. doi: 10.1021/acs.jcim.5c00611. Epub 2025 Aug 6.
2
F NMR Reveals the Dynamics of Substrate Binding and Lid Closure for Iodotyrosine Deiodinase as a Complement to Steady-State Kinetics and Crystallography.F NMR 揭示了碘酪氨酸脱碘酶的底物结合和盖子闭合的动力学，作为对稳态动力学和晶体学的补充。
Biochemistry. 2024 Sep 3;63(17):2225-2232. doi: 10.1021/acs.biochem.4c00243. Epub 2024 Aug 13.
3
Atypical homodimerization revealed by the structure of the (S)-enantioselective haloalkane dehalogenase DmmarA from Mycobacterium marinum.
海分枝杆菌（S）-对映体选择性卤代烷脱卤酶DmmarA的结构揭示的非典型同二聚化
Acta Crystallogr D Struct Biol. 2023 Nov 1;79(Pt 11):956-970. doi: 10.1107/S2059798323006642. Epub 2023 Oct 20.
4
Multimeric structure of a subfamily III haloalkane dehalogenase-like enzyme solved by combination of cryo-EM and x-ray crystallography.通过 cryo-EM 和 X 射线晶体学组合解决的亚家族 III 卤代烷脱卤酶样酶的多聚体结构。
Protein Sci. 2023 Oct;32(10):e4751. doi: 10.1002/pro.4751.
5
Improvement of XYL10C_∆N catalytic performance through loop engineering for lignocellulosic biomass utilization in feed and fuel industries.通过环工程改善XYL10C_∆N的催化性能以用于饲料和燃料行业的木质纤维素生物质利用
Biotechnol Biofuels. 2021 Oct 1;14(1):195. doi: 10.1186/s13068-021-02044-3.
6
Structures of hyperstable ancestral haloalkane dehalogenases show restricted conformational dynamics.超稳定祖先卤代烷脱卤酶的结构显示出受限的构象动力学。
Comput Struct Biotechnol J. 2020 Jun 19;18:1497-1508. doi: 10.1016/j.csbj.2020.06.021. eCollection 2020.
7
Structural and catalytic effects of surface loop-helix transplantation within haloalkane dehalogenase family.卤代烷脱卤酶家族中表面环-螺旋移植的结构和催化效应
Comput Struct Biotechnol J. 2020 Jun 3;18:1352-1362. doi: 10.1016/j.csbj.2020.05.019. eCollection 2020.
8
A Haloalkane Dehalogenase from Saccharomonospora viridis Strain DSM 43017, a Compost Bacterium with Unusual Catalytic Residues, Unique ()-Enantiopreference, and High Thermostability.一株堆肥细菌中具有独特催化残基、独特 ()-对映体选择性和高热稳定性的绿色糖单孢菌 Haloalkane 脱卤酶。
Appl Environ Microbiol. 2020 Aug 18;86(17). doi: 10.1128/AEM.02820-19.
9
Deciphering the Structural Basis of High Thermostability of Dehalogenase from Psychrophilic Bacterium sp. ELB17.解析嗜冷菌ELB17脱卤酶高热稳定性的结构基础
Microorganisms. 2019 Oct 28;7(11):498. doi: 10.3390/microorganisms7110498.
10
Dehalogenases: From Improved Performance to Potential Microbial Dehalogenation Applications.脱卤酶：从提高性能到潜在的微生物脱卤应用。
Molecules. 2018 May 7;23(5):1100. doi: 10.3390/molecules23051100.