García-Osogobio Sandra, Téllez-Avila Félix I, Takahashi-Monroy Takeshi
Departamento de Cirugía, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, DF México.
Acta Gastroenterol Latinoam. 2010 Jun;40(2):142-6.
The ileal pouch-anal anastomosis (IPAA) and ileorectal anastomosis (IRA) are the preferred surgical methods in patients with familial adenomatous polyposis (FAP).
To describe the results obtained from the surgical treatment in patients with FAP related to morbidity, mortality, rectal cancer and overall survival.
We studied a retrospective cohort including all patients operated on with IPAA or IRA for FAP during the period of 1969 to 2000 at the Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran.
Twenty-six patients were included. IRA was performed in 9 patients and IPAA in 17. Surgical morbidity was observed in 5 patients (19.2%). Mean postoperative follow-up was 68.8 +/- 58.8 months (median 52.5 months, range 0-240 months). Functional results were similar in both groups. The five year survival in patients with IPAA and IRA was 100% and 55.6%, respectively (P = 0.035).
In our institution, postoperative morbidity and mortality in patients with FAP are similar to those published in the literature. IPAA seems to offer better results related to survival with similar functional results and postoperative complications.
回肠储袋肛管吻合术（IPAA）和回肠直肠吻合术（IRA）是家族性腺瘤性息肉病（FAP）患者的首选手术方法。
描述FAP患者手术治疗在发病率、死亡率、直肠癌及总生存率方面的结果。
我们研究了一个回顾性队列，包括1969年至2000年期间在萨尔瓦多·苏比拉án国家医学与营养科学研究所接受IPAA或IRA手术治疗FAP的所有患者。
纳入26例患者。9例行IRA手术，17例行IPAA手术。5例（19.2%）出现手术并发症。术后平均随访时间为68.8±58.8个月（中位数52.5个月，范围0 - 240个月）。两组功能结果相似。IPAA组和IRA组患者的五年生存率分别为100%和55.6%（P = 0.035）。
在我们机构，FAP患者的术后发病率和死亡率与文献报道相似。IPAA似乎在生存率方面有更好的结果，功能结果和术后并发症相似。
