Department of Urologic Surgery, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA.
J Urol. 2010 Aug;184(2):659-64. doi: 10.1016/j.juro.2010.03.059.
We determined whether age, gender, body mass index, number of stones, stone location or total stone diameter could independently predict stone-free rates after extracorporeal shock wave lithotripsy in children.
We reviewed 149 patients 3 to 17 years old undergoing shock wave lithotripsy between 2001 and 2008. Cases were retrieved from a regional shock wave lithotripsy database. Variables analyzed included age, gender, body mass index, number of shocks delivered, stone location, number of stones and total stone diameter. Stone-free status on followup imaging at 2 weeks to 3 months was considered a successful outcome.
Of 149 patients 32 had multiple stones. After shock wave lithotripsy 106 patients (71%) were stone-free, 12 (8%) required a repeat procedure and 31 (21%) had residual fragments. Number of stones per patient ranged from 1 to 18 (mean +/- SD 2.14 +/- 2.60). Mean +/- SD number of stones was 1.87 +/- 2.42 in successfully treated patients and 2.81 +/- 2.92 in those with treatment failure (p = 0.065). Total stone diameter ranged from 2 to 90 mm (mean +/- SD 14.03 +/- 16.68). Mean total stone diameter was 11.1 +/- 13.4 mm in successfully treated patients and 21.3 +/- 21.4 mm in those with treatment failure (p <0.005).
To our knowledge we present the first multi-institutional cohort study in children demonstrating no significant relationship between successful outcome and patient age, gender, body mass index, stone location or number of stones. Only total stone diameter independently predicted shock wave lithotripsy success.
我们旨在确定年龄、性别、体重指数、结石数量、结石位置或结石总直径是否可以独立预测儿童体外冲击波碎石后的无石率。
我们回顾了 2001 年至 2008 年间接受冲击波碎石术的 149 名 3 至 17 岁的患者。这些病例是从一个区域性冲击波碎石术数据库中检索出来的。分析的变量包括年龄、性别、体重指数、碎石次数、结石位置、结石数量和结石总直径。将 2 周至 3 个月后的随访影像学上无结石状态视为成功结局。
149 例患者中有 32 例为多发性结石。冲击波碎石术后,106 例(71%)患者无结石,12 例(8%)需要再次治疗,31 例(21%)有残余碎片。每位患者的结石数量为 1 至 18 个(平均值±标准差 2.14±2.60)。成功治疗患者的平均±标准差结石数量为 1.87±2.42 个,治疗失败患者的平均±标准差结石数量为 2.81±2.92 个(p=0.065)。结石总直径为 2 至 90mm(平均值±标准差 14.03±16.68)。成功治疗患者的平均总结石直径为 11.1±13.4mm,治疗失败患者的平均总结石直径为 21.3±21.4mm(p<0.005)。
据我们所知,这是第一份在儿童中进行的多机构队列研究,表明成功结局与患者年龄、性别、体重指数、结石位置或结石数量之间没有显著关系。只有结石总直径独立预测了冲击波碎石术的成功。