Department of Orthopaedics, Norwegian research centre for Active Rehabilitation (NAR), Oslo University Hospital, Oslo, Norway.
Br J Sports Med. 2011 Jun;45(7):583-8. doi: 10.1136/bjsm.2010.073130. Epub 2010 Jul 20.
There are conflicting results in the literature regarding the association between radiographic knee osteoarthritis (OA) and symptoms and function in subjects with previous anterior cruciate ligament (ACL) reconstruction.
To investigate the associations between radiographic tibiofemoral knee OA and knee pain, symptoms, function and knee-related quality of life (QOL) 10-15 years after ACL reconstruction.
Cross-sectional study.
258 subjects were consecutively included at the time of ACL reconstruction and followed up prospectively. The authors included the Knee Injury and Osteoarthritis Outcome Score to evaluate knee pain, other symptoms (symptoms), activities of daily living and sport and recreation (Sport/Rec) and QOL. The subjects underwent standing radiographs 10-15 years after the ACL reconstruction. The radiographs were graded with the Kellgren and Lawrence (K&L) classification (grade 0-4).
210 subjects (81%) consented to participate in the 10-15-year follow-up. Radiographic knee OA (K&L ≥ grade 2) was detected in 71%, and 24% showed moderate or severe radiographic knee OA (K&L grades 3 and 4). No significant associations were detected between radiographic knee OA (K&L grade ≥ 2) and pain, function or QOL, respectively, but subjects with radiographic knee OA showed significantly increased symptoms. Severe radiographic knee OA (K&L grade 4) was significantly associated with more pain, symptoms, impaired Sport/Rec and reduced QOL.
Subjects with radiographic knee OA showed significantly more symptoms than those without OA, and subjects with severe radiographic knee OA had significantly more pain, impaired function and reduced quality of life than those without radiographic knee OA 10-15 years after ACL reconstruction.
关于既往前交叉韧带（ACL）重建患者的放射学膝关节骨关节炎（OA）与症状和功能之间的关系，文献中存在相互矛盾的结果。
研究 ACL 重建 10-15 年后放射学胫股膝关节 OA 与膝关节疼痛、症状、功能和膝关节相关生活质量（QOL）之间的相关性。
横断面研究。
连续纳入 258 例 ACL 重建时的受试者，并进行前瞻性随访。作者使用膝关节损伤和骨关节炎结果评分（KOOS）评估膝关节疼痛、其他症状（症状）、日常生活活动和运动及娱乐（Sport/Rec）以及 QOL。受试者在 ACL 重建后 10-15 年接受站立位放射摄影。放射摄影采用 Kellgren 和 Lawrence（K&L）分级（0-4 级）进行分级。
210 例受试者（81%）同意参加 10-15 年随访。放射学膝关节 OA（K&L≥2 级）检出率为 71%，24%显示中度或重度放射学膝关节 OA（K&L 分级 3 和 4 级）。放射学膝关节 OA（K&L 分级≥2 级）与疼痛、功能或 QOL 之间无显著相关性，但放射学膝关节 OA 患者的症状明显增加。严重放射学膝关节 OA（K&L 分级 4 级）与更多疼痛、症状、运动及娱乐受损和 QOL 降低显著相关。
放射学膝关节 OA 患者的症状明显多于无 OA 患者，严重放射学膝关节 OA 患者的疼痛、功能障碍和生活质量降低程度明显高于无放射学膝关节 OA 患者，ACL 重建后 10-15 年。
