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提高磁感应断层成像图像质量的方法。

Approaches for improving image quality in magnetic induction tomography.

机构信息

Carleton University, Ottawa, K1S 5B6, Canada.

出版信息

Physiol Meas. 2010 Aug;31(8):S147-56. doi: 10.1088/0967-3334/31/8/S12. Epub 2010 Jul 21.

Abstract

Magnetic induction tomography (MIT) is a contactless and non-invasive method for imaging the passive electrical properties of objects. Measuring the weak signal produced by eddy currents within biological soft tissues can be challenging in the presence of noise and the large signals resulting from the direct excitation-detection coil coupling. To detect haemorrhagic stroke in the brain, for instance, high measurement accuracy is required to enable images with enough contrast to differentiate between normal and haemorrhaged brain tissues. The reconstructed images are often very sensitive to inevitable measurement noise from the environment, system instabilities and patient-related artefacts such as movement and sweating. We propose methods for mitigating signal noise and improving image reconstruction. We evaluated and compared the use of a range wavelet transforms for signal denoising. Adaptive regularization methods including L-curve, generalized cross validation (GCV) and noise estimation were also compared. We evaluated all these described methods with measurements of in vitro tissues resembling a peripheral haemorrhagic cerebral stroke created by placing a bio-membrane package filled with 10 ml blood in a swine brain of 100 ml. We show that wavelet packet denoising combined with adaptive regularization can improve the quality of reconstructed images.

摘要

磁感应断层成像(MIT)是一种用于对物体的无源电特性进行成像的非接触式和非侵入式方法。在存在噪声和直接激励-检测线圈耦合产生的大信号的情况下,测量生物软组织内涡流产生的微弱信号可能具有挑战性。例如,为了检测大脑中的出血性中风,需要高测量精度来实现具有足够对比度的图像,以便区分正常和出血的脑组织。重建的图像通常对环境不可避免的测量噪声、系统不稳定性以及与患者相关的伪影(如运动和出汗)非常敏感。我们提出了用于减轻信号噪声和改善图像重建的方法。我们评估并比较了一系列用于信号去噪的小波变换的使用。还比较了包括 L 曲线、广义交叉验证(GCV)和噪声估计在内的自适应正则化方法。我们使用类似于由充满 10 毫升血液的生物膜包裹的外周出血性脑卒中来模拟的体外组织的测量值来评估所有这些描述的方法,该生物膜包裹物放置在 100 毫升猪脑内。我们表明,小波包去噪与自适应正则化相结合可以提高重建图像的质量。

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