1例经R-CHOP化疗有效治疗的原发性肝胆恶性淋巴瘤

[A case of primary hepato-biliary malignant lymphoma effectively treated with R-CHOP chemotherapy].

作者信息

Hiramoto Keiichiro, Kuroki Michio, Shoji Hirokazu, Matsumura Yoshifumi, Miura Atsushi, Kikuchi Yoshifumi, Hirakawa Hidetoshi, Kimura Jun, Matsuda Mikio

机构信息

Department of Gastroenterology, Yamagata City Hospital Saiseikan.

出版信息

Gan To Kagaku Ryoho. 2010 Jul;37(7):1345-8.

PMID:20647724

Abstract

A 65-year-old man was admitted to our hospital because of obstructive jaundice caused by a mass extending in the porta hepatis, neck of gall bladder and extrahepatic bile duct. The specimens obtained with ultrasound-guided needle biopsy showed malignant lymphoma (diffuse large B-cell lymphoma: DLBCL). CHOP with Rituximab therapy (R-CHOP therapy) was performed. The treatment resulted in remarkable reduction of the tumor size and improvement of the biliary stenosis. We should take into consideration malignant lymphoma when we see a patient with a tumor of the hepato-biliary system.

摘要

一名65岁男性因肝门部、胆囊颈部及肝外胆管肿物导致梗阻性黄疸入院。超声引导下经皮穿刺活检标本显示为恶性淋巴瘤（弥漫性大B细胞淋巴瘤：DLBCL）。给予利妥昔单抗联合CHOP方案治疗（R-CHOP方案）。治疗后肿瘤大小显著缩小，胆管狭窄改善。对于肝胆系统肿瘤患者，应考虑到恶性淋巴瘤的可能。