Lönnemark M, Hemmingsson A, Bach-Gansmo T, Hagberg H, Magnusson A, Gundersen H G, Nyman R
Department of Diagnostic Radiology, Uppsala University, Sweden.
Acta Radiol. 1991 May;32(3):232-8.
Non-biodegradable superparamagnetic particles, in plain and viscous aqueous suspensions, were used as an oral contrast medium in 34 patients with known or suspected malignant lymphoma. The contrast effect, the occurrence of artifacts, and the distribution were evaluated in the plain and the viscous aqueous suspensions, and the diagnostic information received from abdominal MR examinations performed without bowel contrast medium was compared with that of post-contrast examinations. Magnetic particles in the concentration of 0.5 g/l displayed a good contrast effect at 0.5 T, and helped in differentiating the intestine from adjacent tissues, resulting in increased diagnostic information in abdominal MR imaging. In the patients given the viscous aqueous suspension the occurrence of artifacts caused by the magnetic particles decreased considerably, and the distribution was homogeneous and improved compared with that in patients given the plain aqueous suspension.
不可生物降解的超顺磁性颗粒，以普通和粘性水性悬浮液的形式，被用作34例已知或疑似恶性淋巴瘤患者的口服造影剂。在普通和粘性水性悬浮液中评估了造影效果、伪影的发生情况和分布，并将未使用肠道造影剂进行的腹部磁共振检查所获得的诊断信息与造影后检查的诊断信息进行了比较。浓度为0.5 g/l的磁性颗粒在0.5 T时显示出良好的造影效果，有助于将肠道与相邻组织区分开来，从而增加了腹部磁共振成像中的诊断信息。在给予粘性水性悬浮液的患者中，由磁性颗粒引起的伪影发生率显著降低，与给予普通水性悬浮液的患者相比，分布均匀且有所改善。
